Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2010-9-6
pubmed:abstractText
Monomethylmercury (CH3Hg+ and its complexes; MeHg hereafter) is a known developmental neurotoxin. Recent studies have shown that rice (Oryza sativa L.) grain grown from mercury (Hg) mining areas may contain elevated MeHg concentrations, raising concerns over the health of local residents who consume rice on a daily basis. An analytical method employing high performance liquid chromatography (HPLC)--inductively coupled plasma mass spectrometry (ICP-MS) following enzymatic hydrolysis was developed to analyze the speciation of MeHg in uncooked and cooked white rice grain grown from the vicinity of a Hg mine in China. The results revealed that the MeHg in the uncooked rice is present almost exclusively as CH3Hg-L-cysteinate (CH3HgCys), a complex that is thought to be responsible for the transfer of MeHg across the blood-brain and placental barriers. Although cooking does not change the total Hg or total MeHg concentration in rice, no CH3HgCys is measurable after cooking, suggesting that most, if not all, of the CH3HgCys is converted to other forms of MeHg, the identity and toxicity of which remain elusive.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1873-6424
pubmed:author
pubmed:copyrightInfo
Copyright (c) 2010 Elsevier Ltd. All rights reserved.
pubmed:issnType
Electronic
pubmed:volume
158
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3103-7
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Speciation of methylmercury in rice grown from a mercury mining area.
pubmed:affiliation
Department of Environment and Geography, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't