Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1991-8-15
|
| pubmed:abstractText |
We attempted to reassess the significance of cervicovaginal Papanicolaou smear(s) in identifying adenocarcinoma (AC) by comparing Papanicolaou smears with histopathology in a pool of 188 patients. The first part of study dealt with 95 patients, seen over a 12-yr period (1975-1986), who had tissue diagnosis of cervical or endometrial AC, all with prior papanicolaou smears available. Of the 95 patients, Papanicolaou smears were positive and/or inconclusive for uterine AC in 37 (38.9%) and falsely negative in 58 (61.1%) patients. Of the latter, six were either positive and/or inconclusive for squamous carcinoma and moderate to severe dysplasia; thus, the effective detection rate (sensitivity) for malignancy and related condition of Papanicolaou smears was 45.3% (43 of 95). The second part of the study concerned the analysis of 130 patients with 148 Papanicolaou smear in whom cytologic diagnosis positive and/or inconclusive for AC was made during the same study period. Tissue diagnoses were available in 107 of these as follows: AC and glandular hyperplasia in 66 patients (61.7% predictive value), with 11 (10.3%) from extrauterine sources; squamous carcinoma in 12 and moderate to severe dysplasia in 5, totalling 17 patients (15.9%); miscellaneous conditions (polyps, radiation change, and glandular atrophy) in 11 patients (10.3%); and no pathologic change in 13 patients (12.1%). The effective predictive value of positive and/or inconclusive Papanicolaou smears for all malignancy and related states is 77.6%.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
8755-1039
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
7
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
119-24
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:2065563-Adenocarcinoma,
pubmed-meshheading:2065563-Adult,
pubmed-meshheading:2065563-Aged,
pubmed-meshheading:2065563-Aged, 80 and over,
pubmed-meshheading:2065563-False Negative Reactions,
pubmed-meshheading:2065563-False Positive Reactions,
pubmed-meshheading:2065563-Female,
pubmed-meshheading:2065563-Humans,
pubmed-meshheading:2065563-Middle Aged,
pubmed-meshheading:2065563-Neoplasm Staging,
pubmed-meshheading:2065563-Predictive Value of Tests,
pubmed-meshheading:2065563-Retrospective Studies,
pubmed-meshheading:2065563-Uterine Neoplasms,
pubmed-meshheading:2065563-Vaginal Smears
|
| pubmed:year |
1991
|
| pubmed:articleTitle |
Adenocarcinomas in the cervicovaginal Papanicolaou smear: analysis of a 12-year experience.
|
| pubmed:affiliation |
Harris County Hospital District, Houston, TX.
|
| pubmed:publicationType |
Journal Article
|