rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2010-7-23
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pubmed:abstractText |
Tumor progression is influenced by the microenvironment. We found stem cells are recruited to malignant mesothelioma spheroids. We aimed to determine if stem cell recruitment depends on the chemokine SDF1, and if inhibition of the cognate receptor CXCR4 affects tumor growth.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Ly,
http://linkedlifedata.com/resource/pubmed/chemical/CXCR4 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CXCL12,
http://linkedlifedata.com/resource/pubmed/chemical/Cxcl12 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Heterocyclic Compounds,
http://linkedlifedata.com/resource/pubmed/chemical/JM 3100,
http://linkedlifedata.com/resource/pubmed/chemical/Ly6a protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, CXCR4
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1791-7530
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2153-60
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pubmed:meshHeading |
pubmed-meshheading:20651364-Animals,
pubmed-meshheading:20651364-Antigens, Ly,
pubmed-meshheading:20651364-Cell Movement,
pubmed-meshheading:20651364-Cell Proliferation,
pubmed-meshheading:20651364-Chemokine CXCL12,
pubmed-meshheading:20651364-Heterocyclic Compounds,
pubmed-meshheading:20651364-Membrane Proteins,
pubmed-meshheading:20651364-Mesenchymal Stem Cells,
pubmed-meshheading:20651364-Mesothelioma,
pubmed-meshheading:20651364-Mice,
pubmed-meshheading:20651364-Mice, Inbred C57BL,
pubmed-meshheading:20651364-Receptors, CXCR4,
pubmed-meshheading:20651364-Spheroids, Cellular
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pubmed:year |
2010
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pubmed:articleTitle |
SDF1/CXCL12 is involved in recruitment of stem-like progenitor cells to orthotopic murine malignant mesothelioma spheroids.
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pubmed:affiliation |
Department of Pathology and Laboratory Medicine, Brown University, Box G-8235, Providence, RI 02912, USA. Bonnie_Lau@brown.edu
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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