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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2010-9-17
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pubmed:abstractText |
Tumor necrosis factor receptor-associated factors (TRAFs) are cytoplasmic adaptor proteins for the TNF/interleukin-1/Toll-like receptor superfamily. Ligands of this family comprise multiple important cytokines such as TNF?, CD40L, and interleukin-1? that promote chronic inflammatory diseases such as atherosclerosis. We recently reported overexpression of TRAF5 in murine and human atheromata and that TRAF5 promotes inflammatory functions of cultured endothelial cells and macrophages.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1524-4571
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pubmed:author |
pubmed-author:AichelePeterP,
pubmed-author:BodeChristophC,
pubmed-author:ColbergChristianC,
pubmed-author:ErnstSandraS,
pubmed-author:HilgendorfIngoI,
pubmed-author:HoppeNatalieN,
pubmed-author:MünkelChristianC,
pubmed-author:MissiouAnnaA,
pubmed-author:NakanoHiroyasuH,
pubmed-author:RudolfPhilippP,
pubmed-author:SommerBenjaminB,
pubmed-author:StachonPeterP,
pubmed-author:VaroNereaN,
pubmed-author:WalterCarinaC,
pubmed-author:WolfDennisD,
pubmed-author:ZirlikAndreasA
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pubmed:issnType |
Electronic
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pubmed:day |
17
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pubmed:volume |
107
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
757-66
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pubmed:meshHeading |
pubmed-meshheading:20651286-Aged,
pubmed-meshheading:20651286-Animals,
pubmed-meshheading:20651286-Atherosclerosis,
pubmed-meshheading:20651286-Cell Differentiation,
pubmed-meshheading:20651286-Cell Movement,
pubmed-meshheading:20651286-Cells, Cultured,
pubmed-meshheading:20651286-Coronary Disease,
pubmed-meshheading:20651286-Female,
pubmed-meshheading:20651286-Foam Cells,
pubmed-meshheading:20651286-Follow-Up Studies,
pubmed-meshheading:20651286-Humans,
pubmed-meshheading:20651286-Inflammation,
pubmed-meshheading:20651286-Macrophages,
pubmed-meshheading:20651286-Male,
pubmed-meshheading:20651286-Mice,
pubmed-meshheading:20651286-Mice, Inbred C57BL,
pubmed-meshheading:20651286-Mice, Knockout,
pubmed-meshheading:20651286-Middle Aged,
pubmed-meshheading:20651286-Pregnancy,
pubmed-meshheading:20651286-TNF Receptor-Associated Factor 5
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pubmed:year |
2010
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pubmed:articleTitle |
TRAF5 deficiency accelerates atherogenesis in mice by increasing inflammatory cell recruitment and foam cell formation.
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pubmed:affiliation |
Department of Cardiology, University of Freiburg, Germany.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Research Support, Non-U.S. Gov't
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