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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2010-7-21
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pubmed:abstractText |
It has been postulated that the induced suppressor of cytokine signalling (SOCS) protein inhibits the signalling pathway through the association with a variety of tyrosine kinase proteins, and decelerates or inhibits the progression of cirrhosis and hepatocellular carcinoma (HCC). The purpose of this study was to investigate the expression of SOCS1 gene in HCC and explore the potential molecular mechanisms.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1424-3997
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
140
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
w13065
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pubmed:dateRevised |
2011-2-15
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pubmed:meshHeading |
pubmed-meshheading:20648401-Carcinoma, Hepatocellular,
pubmed-meshheading:20648401-Cell Transformation, Neoplastic,
pubmed-meshheading:20648401-CpG Islands,
pubmed-meshheading:20648401-DNA Methylation,
pubmed-meshheading:20648401-Down-Regulation,
pubmed-meshheading:20648401-Epigenesis, Genetic,
pubmed-meshheading:20648401-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:20648401-Humans,
pubmed-meshheading:20648401-Liver,
pubmed-meshheading:20648401-Liver Cirrhosis,
pubmed-meshheading:20648401-Liver Neoplasms,
pubmed-meshheading:20648401-Promoter Regions, Genetic,
pubmed-meshheading:20648401-RNA, Messenger,
pubmed-meshheading:20648401-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:20648401-Suppressor of Cytokine Signaling Proteins,
pubmed-meshheading:20648401-Taiwan
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pubmed:year |
2010
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pubmed:articleTitle |
Epigenetic alteration of the SOCS1 gene in hepatocellular carcinoma.
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pubmed:affiliation |
Department of Surgical Pathology, Changhua Christian Hospital, Taiwan.
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pubmed:publicationType |
Journal Article
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