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rdf:type |
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lifeskim:mentions |
umls-concept:C0011209,
umls-concept:C0012854,
umls-concept:C0021492,
umls-concept:C0025202,
umls-concept:C0030705,
umls-concept:C0205470,
umls-concept:C0221920,
umls-concept:C0281722,
umls-concept:C0871261,
umls-concept:C1420066,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C1707455,
umls-concept:C2911692
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pubmed:issue |
15
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pubmed:dateCreated |
2010-7-30
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pubmed:abstractText |
Prior studies show that i.m. injection of xenogeneic orthologues of melanosomal antigens (tyrosinase, gp100) induces CD8(+) T-cell responses to the syngeneic protein. To further define the optimal vaccination strategy, we conducted a pilot clinical trial comparing i.m. injection with particle-mediated epidermal delivery (PMED).
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Heterophile,
http://linkedlifedata.com/resource/pubmed/chemical/Cancer Vaccines,
http://linkedlifedata.com/resource/pubmed/chemical/DNA,
http://linkedlifedata.com/resource/pubmed/chemical/HLA-A*02:01 antigen,
http://linkedlifedata.com/resource/pubmed/chemical/HLA-A Antigens,
http://linkedlifedata.com/resource/pubmed/chemical/HLA-A2 Antigen,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Peptides,
http://linkedlifedata.com/resource/pubmed/chemical/SILV protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Si protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Vaccines, DNA,
http://linkedlifedata.com/resource/pubmed/chemical/gp100(280-288) melanoma antigen...,
http://linkedlifedata.com/resource/pubmed/chemical/gp100 Melanoma Antigen
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1078-0432
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pubmed:author |
pubmed-author:AdamowMatthewM,
pubmed-author:BewkesBarrett BBB,
pubmed-author:CarvajalRichard DRD,
pubmed-author:ChapmanPaul BPB,
pubmed-author:GallardoHumilidad FHF,
pubmed-author:GinsbergBrian ABA,
pubmed-author:HoughtonAlan NAN,
pubmed-author:MuZhenyuZ,
pubmed-author:PanageasKatherine SKS,
pubmed-author:RasalanTeresa STS,
pubmed-author:RomanRuth-AnnRA,
pubmed-author:SchwartzGary KGK,
pubmed-author:TandonSapnaS,
pubmed-author:TerzulliStephanie LSL,
pubmed-author:WolchokJedd DJD,
pubmed-author:YuanJianda DJD
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pubmed:copyrightInfo |
(c) 2010 AACR.
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4057-65
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:20647477-Administration, Intranasal,
pubmed-meshheading:20647477-Adult,
pubmed-meshheading:20647477-Aged,
pubmed-meshheading:20647477-Animals,
pubmed-meshheading:20647477-Antigens, Heterophile,
pubmed-meshheading:20647477-Biolistics,
pubmed-meshheading:20647477-CD8-Positive T-Lymphocytes,
pubmed-meshheading:20647477-Cancer Vaccines,
pubmed-meshheading:20647477-DNA,
pubmed-meshheading:20647477-Female,
pubmed-meshheading:20647477-HLA-A Antigens,
pubmed-meshheading:20647477-HLA-A2 Antigen,
pubmed-meshheading:20647477-Humans,
pubmed-meshheading:20647477-Kaplan-Meier Estimate,
pubmed-meshheading:20647477-Male,
pubmed-meshheading:20647477-Melanoma,
pubmed-meshheading:20647477-Membrane Glycoproteins,
pubmed-meshheading:20647477-Mice,
pubmed-meshheading:20647477-Middle Aged,
pubmed-meshheading:20647477-Neoplasm Staging,
pubmed-meshheading:20647477-Peptides,
pubmed-meshheading:20647477-Pilot Projects,
pubmed-meshheading:20647477-Vaccines, DNA,
pubmed-meshheading:20647477-gp100 Melanoma Antigen
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pubmed:year |
2010
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pubmed:articleTitle |
Immunologic response to xenogeneic gp100 DNA in melanoma patients: comparison of particle-mediated epidermal delivery with intramuscular injection.
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pubmed:affiliation |
Ludwig Center for Cancer Immunotherapy, Immunology Program, Sloan-Kettering Institute, 1275 York Avenue, New York, NY 10065, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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