Source:http://linkedlifedata.com/resource/pubmed/id/20647034
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2011-2-4
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pubmed:abstractText |
Traditional materials used as in vitro cell culture substrates are rigid and flat surfaces that lack the exquisite nano- and micro-scale features of the in vivo extracellular environment. While these surfaces can be coated with harvested extracellular matrix (ECM) proteins to partially recapitulate the bio-instructive nature of the ECM, these harvested proteins often exhibit large batch-to-batch variability and can be difficult to customize for specific biological studies. In contrast, recombinant protein technology can be utilized to synthesize families of 3 dimensional protein-engineered biomaterials that are cyto-compatible, reproducible, and fully customizable.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0006-3002
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pubmed:author | |
pubmed:copyrightInfo |
2010 Elsevier B.V. All rights reserved.
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pubmed:issnType |
Print
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pubmed:volume |
1810
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
339-49
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pubmed:dateRevised |
2011-9-26
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pubmed:meshHeading |
pubmed-meshheading:20647034-Animals,
pubmed-meshheading:20647034-Biocompatible Materials,
pubmed-meshheading:20647034-Biomimetics,
pubmed-meshheading:20647034-Extracellular Matrix,
pubmed-meshheading:20647034-Humans,
pubmed-meshheading:20647034-Nanostructures,
pubmed-meshheading:20647034-Peptide Fragments,
pubmed-meshheading:20647034-Protein Engineering
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pubmed:year |
2011
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pubmed:articleTitle |
Protein-engineered biomaterials: nanoscale mimics of the extracellular matrix.
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pubmed:affiliation |
Department of Materials Science and Engineering, Stanford University, Stanford, CA 94305-4045, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Review,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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