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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2010-7-20
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pubmed:abstractText |
Septic cavernous sinus thrombosis (CST) is an uncommon clinical syndrome. Although Staphylococcus aureus (S aureus) is the most common bacterial pathogen causing CST, it is infrequent as a cause of meningitis. We report the first case of CST and meningitis from Bengaluru, Karnataka, caused by community-acquired epidemic methicillin resistant Staphylococcus aureus-15 (EMRSA-15), in a previously healthy individual without known risk factors; the patient recovered following treatment with vancomycin. The isolate was genotyped as belonging to staphylococcal cassette chromosome mec type IV and sequence type 22 and carried the panton-valentine leucocidin gene. It is the first Indian EMRSA-15 disease isolate from a case of meningitis. EMRSA-15 has been a major problem in hospitals in UK and it is a cause for great concern in Indian hospitals too.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1998-3646
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
255-7
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pubmed:meshHeading |
pubmed-meshheading:20644319-Adolescent,
pubmed-meshheading:20644319-Anti-Bacterial Agents,
pubmed-meshheading:20644319-Bacterial Toxins,
pubmed-meshheading:20644319-Bacterial Typing Techniques,
pubmed-meshheading:20644319-Cavernous Sinus Thrombosis,
pubmed-meshheading:20644319-Community-Acquired Infections,
pubmed-meshheading:20644319-DNA, Bacterial,
pubmed-meshheading:20644319-DNA Fingerprinting,
pubmed-meshheading:20644319-Electrophoresis, Gel, Pulsed-Field,
pubmed-meshheading:20644319-Exotoxins,
pubmed-meshheading:20644319-Genotype,
pubmed-meshheading:20644319-Humans,
pubmed-meshheading:20644319-India,
pubmed-meshheading:20644319-Leukocidins,
pubmed-meshheading:20644319-Male,
pubmed-meshheading:20644319-Meningitis, Bacterial,
pubmed-meshheading:20644319-Methicillin-Resistant Staphylococcus aureus,
pubmed-meshheading:20644319-Staphylococcal Infections,
pubmed-meshheading:20644319-Vancomycin,
pubmed-meshheading:20644319-Virulence Factors
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pubmed:articleTitle |
A variant epidemic methicillin resistant Staphylococcus aureus-15 cavernous sinus thrombosis and meningitis: a rare occurrence with unusual presentation.
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pubmed:affiliation |
Department of Hospital Infection Surveillance System, Neuromicrobiology, Bengaluru 560029, India.
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pubmed:publicationType |
Journal Article,
Case Reports
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