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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2010-7-20
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pubmed:abstractText |
To compare the "take" rates of skin grafts between myeloid-selective hypoxia-inducible factor (HIF) 1alpha knockout (KO) and wild-type (WT) mice. Production of the alpha subunit of HIF-1alpha is increased in healing wounds, which stimulates expression of vascular endothelial growth factor (VEGF) to promote angiogenesis. Therefore, the take rate of skin grafts may be closely associated with the presence or absence of HIF-1alpha production in the recipient bed.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1538-361X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
136
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
720-3
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pubmed:meshHeading |
pubmed-meshheading:20644069-Animals,
pubmed-meshheading:20644069-Biological Markers,
pubmed-meshheading:20644069-Disease Models, Animal,
pubmed-meshheading:20644069-Follow-Up Studies,
pubmed-meshheading:20644069-Graft Rejection,
pubmed-meshheading:20644069-Graft Survival,
pubmed-meshheading:20644069-Granulation Tissue,
pubmed-meshheading:20644069-Hypoxia-Inducible Factor 1, alpha Subunit,
pubmed-meshheading:20644069-Male,
pubmed-meshheading:20644069-Mice,
pubmed-meshheading:20644069-Mice, Inbred C57BL,
pubmed-meshheading:20644069-Mice, Knockout,
pubmed-meshheading:20644069-Myeloid Cells,
pubmed-meshheading:20644069-Predictive Value of Tests,
pubmed-meshheading:20644069-Probability,
pubmed-meshheading:20644069-Random Allocation,
pubmed-meshheading:20644069-Skin,
pubmed-meshheading:20644069-Skin Transplantation,
pubmed-meshheading:20644069-Time Factors,
pubmed-meshheading:20644069-Tissue and Organ Harvesting,
pubmed-meshheading:20644069-Wound Healing
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pubmed:year |
2010
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pubmed:articleTitle |
Skin graft take rates, granulation, and epithelialization: dependence on myeloid cell hypoxia-inducible factor 1alpha.
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pubmed:affiliation |
Department of Otolaryngology-Head and Neck Surgery, University of Arkansas for Medical Sciences, 4301 W Markham, Slot 543, Little Rock, AR 72205, USA. vuralemrea@uams.edu
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, N.I.H., Extramural
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