rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2010-12-20
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pubmed:abstractText |
OVA-301 is a large randomized trial that showed superiority of trabectedin plus pegylated liposomal doxorubicin (PLD; CentoCor Ortho Biotech Products L.P., Raritan, NJ, USA). over single-agent PLD in 672 patients with relapsed ovarian cancer, particularly in the partially platinum-sensitive subgroup [platinum-free interval (PFI) of 6-12 months]. This superiority has been suggested to be due to the differential impact of subsequent (platinum) therapy.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1569-8041
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pubmed:author |
pubmed-author:ChanSS,
pubmed-author:ColomboNN,
pubmed-author:Filipczyk-CisarzEE,
pubmed-author:HagbergHH,
pubmed-author:KayeS BSB,
pubmed-author:KoneDD,
pubmed-author:LebedinskyCC,
pubmed-author:MonkB JBJ,
pubmed-author:NietoAA,
pubmed-author:ParekhTT,
pubmed-author:ParkY CYC,
pubmed-author:PovedaAA,
pubmed-author:RoyMM,
pubmed-author:SantabárbaraPP,
pubmed-author:TjulandinSS,
pubmed-author:VergoteII
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pubmed:issnType |
Electronic
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
49-58
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pubmed:meshHeading |
pubmed-meshheading:20643863-Adult,
pubmed-meshheading:20643863-Aged,
pubmed-meshheading:20643863-Aged, 80 and over,
pubmed-meshheading:20643863-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:20643863-Dioxoles,
pubmed-meshheading:20643863-Doxorubicin,
pubmed-meshheading:20643863-Drug Administration Schedule,
pubmed-meshheading:20643863-Female,
pubmed-meshheading:20643863-Humans,
pubmed-meshheading:20643863-Middle Aged,
pubmed-meshheading:20643863-Organoplatinum Compounds,
pubmed-meshheading:20643863-Ovarian Neoplasms,
pubmed-meshheading:20643863-Polyethylene Glycols,
pubmed-meshheading:20643863-Recurrence,
pubmed-meshheading:20643863-Tetrahydroisoquinolines,
pubmed-meshheading:20643863-Treatment Outcome
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pubmed:year |
2011
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pubmed:articleTitle |
Trabectedin plus pegylated liposomal doxorubicin in relapsed ovarian cancer delays third-line chemotherapy and prolongs the platinum-free interval.
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pubmed:affiliation |
Section of Medicine, Institute of Cancer Research, The Royal Marsden Hospital, Sutton, Surrey, UK. stan.kaye@rmh.nhs.uk
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study,
Clinical Trial, Phase III
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