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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2010-7-20
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pubmed:abstractText |
Previous studies showed that the assessment of promoter hypermethylation of a limited number of genes in tumor biopsies may identify the majority of colorectal tumors. This study aimed to assess the clinical usefulness of a panel of methylation biomarkers in stool DNA in the identification of colorectal tumors, using methylation-specific melting curve analysis (MS-MCA), a technique that simultaneously analyzes all cytosine-phosphate-guanine (CpG) residues within a promoter.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/DNA,
http://linkedlifedata.com/resource/pubmed/chemical/DNA Modification Methylases,
http://linkedlifedata.com/resource/pubmed/chemical/DNA Repair Enzymes,
http://linkedlifedata.com/resource/pubmed/chemical/MGMT protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/RARB2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Retinoic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Markers, Biological,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Suppressor Proteins
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1938-0674
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pubmed:author |
pubmed-author:AzuaraDanielD,
pubmed-author:BiondoSebastianoS,
pubmed-author:BlancoIgnacioI,
pubmed-author:CapelláGabrielG,
pubmed-author:EstellerManelM,
pubmed-author:GuardiolaJordiJ,
pubmed-author:MoraJosefinaJ,
pubmed-author:MorenoVictorV,
pubmed-author:PeinadoMiguel AngelMA,
pubmed-author:Rodriguez-MorantaFranciscoF,
pubmed-author:Soriano-IzquierdoAntonioA,
pubmed-author:de OcaJavierJ
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pubmed:issnType |
Electronic
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
168-76
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pubmed:meshHeading |
pubmed-meshheading:20643622-Adenocarcinoma,
pubmed-meshheading:20643622-Adenoma,
pubmed-meshheading:20643622-Colorectal Neoplasms,
pubmed-meshheading:20643622-DNA,
pubmed-meshheading:20643622-DNA Methylation,
pubmed-meshheading:20643622-DNA Modification Methylases,
pubmed-meshheading:20643622-DNA Repair Enzymes,
pubmed-meshheading:20643622-Early Detection of Cancer,
pubmed-meshheading:20643622-Feces,
pubmed-meshheading:20643622-Female,
pubmed-meshheading:20643622-Genes, APC,
pubmed-meshheading:20643622-Genes, p16,
pubmed-meshheading:20643622-Humans,
pubmed-meshheading:20643622-Male,
pubmed-meshheading:20643622-Neoplasm Staging,
pubmed-meshheading:20643622-Polymerase Chain Reaction,
pubmed-meshheading:20643622-Promoter Regions, Genetic,
pubmed-meshheading:20643622-Receptors, Retinoic Acid,
pubmed-meshheading:20643622-Sensitivity and Specificity,
pubmed-meshheading:20643622-Tumor Markers, Biological,
pubmed-meshheading:20643622-Tumor Suppressor Proteins
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pubmed:year |
2010
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pubmed:articleTitle |
Novel methylation panel for the early detection of colorectal tumors in stool DNA.
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pubmed:affiliation |
Translational Research Laboratory, Institut Català d'Oncologia-IDIBELL, Barcelona, Spain.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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