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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2010-10-5
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pubmed:abstractText |
Breast cancer currently accounts for more than one-quarter of all female cancers and, despite the great progress in treatment observed in the past few years, the need for identification of new gene targets that can be used for diagnosis, prognosis and therapy is evident. A previous study identified the transcription factor NR4A1 as a gene upregulated in primary breast cancer compared with normal tissue by microarray analysis and sequencing technologies. The purpose of the study was to identify the role of NR4A1 in normal mammary epithelial and breast cancer cell biology.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Focal Adhesion Kinase 1,
http://linkedlifedata.com/resource/pubmed/chemical/MAPK1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinase 1,
http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinase 3,
http://linkedlifedata.com/resource/pubmed/chemical/NR4A1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Nuclear Receptor Subfamily 4...,
http://linkedlifedata.com/resource/pubmed/chemical/PTK2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors
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pubmed:status |
MEDLINE
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pubmed:issn |
1465-542X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
R51
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pubmed:meshHeading |
pubmed-meshheading:20642837-Blotting, Western,
pubmed-meshheading:20642837-Breast Neoplasms,
pubmed-meshheading:20642837-Cell Adhesion,
pubmed-meshheading:20642837-Cell Line,
pubmed-meshheading:20642837-Cell Line, Tumor,
pubmed-meshheading:20642837-Cell Movement,
pubmed-meshheading:20642837-Cell Survival,
pubmed-meshheading:20642837-Epithelial Cells,
pubmed-meshheading:20642837-Female,
pubmed-meshheading:20642837-Focal Adhesion Kinase 1,
pubmed-meshheading:20642837-Gene Expression Profiling,
pubmed-meshheading:20642837-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:20642837-Gene Regulatory Networks,
pubmed-meshheading:20642837-Humans,
pubmed-meshheading:20642837-Immunohistochemistry,
pubmed-meshheading:20642837-Mammary Glands, Human,
pubmed-meshheading:20642837-Mitogen-Activated Protein Kinase 1,
pubmed-meshheading:20642837-Mitogen-Activated Protein Kinase 3,
pubmed-meshheading:20642837-Nuclear Receptor Subfamily 4, Group A, Member 1,
pubmed-meshheading:20642837-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:20642837-Tissue Array Analysis,
pubmed-meshheading:20642837-Transcription Factors
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pubmed:year |
2010
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pubmed:articleTitle |
Dissecting the transcriptional networks underlying breast cancer: NR4A1 reduces the migration of normal and breast cancer cell lines.
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pubmed:affiliation |
University of Oxford Branch, Ludwig Institute for Cancer Research, Old Road Campus, Off Roosevelt Drive, Oxford OX3 7DQ, UK. a.alexopoulou@prion.ucl.ac.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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