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pubmed-article:20640990pubmed:abstractTextThe effect of interleukin-11 (IL-11) on transforming growth factor-ß (TGF-ß) is controversial and has not been examined in renal diseases. In this study, we (i) characterised the up-regulation of TGF-ß1, phospho-p38 MAPK (p-p38 MAPK) and extracellular matrix during pathogenesis of glomerulonephritis and (ii) examined the effect of rhIL-11 on these processes in vivo.lld:pubmed
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pubmed-article:20640990pubmed:articleTitleEffect of IL-11 on glomerular expression of TGF-beta and extracellular matrix in nephrotoxic nephritis in Wistar Kyoto rats.lld:pubmed
pubmed-article:20640990pubmed:affiliationImperial College Kidney and Transplant Institute, Division of Medicine, Imperial College London, London, UK. Victoria.a.kumar@kp.orglld:pubmed
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