Linked Life Data

20640808

Source:http://linkedlifedata.com/resource/pubmed/id/20640808

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2010-7-19
pubmed:abstractText
The genus flavivirus in the family Flaviviridae consists of many arthropod transmitted human pathogens. siRNA is a novel strategy used for controlling the gene expression of flavivirus. These are 20-25 nucleotide long dsRNA molecules that target genes at expression level. Nine flavivirus genomes were used to in silico identify the siRNA. Twenty three siRNAs were identified in the 5' UTR and capsid protein encoding gene from flavivirus. These siRNA can be useful to knockdown the flavivirus and it might also be helpful for constructing live attenuated vaccine.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1913-2751
pubmed:author
pubmed:issnType
Print
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
298-302
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
High throughput prediction and analysis of small interfering RNA from the 5'UTR and capsid genes of flavivirus through in silico strategies.
pubmed:affiliation
Bioinformatics centre, Biotech Park, Sector-G, Jankipuram, Lucknow, India. psomvanshi@gmail.com
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't