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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2010-10-7
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pubmed:abstractText |
The clinical characteristics of 357 patients with hemoglobin H (HbH) disease from the Guangxi province of Southern China were studied. One hundred and ninety-one (53.3%) patients were diagnosed with HbH-Constant Spring, 19 were diagnosed with HbH Westmead. Ten patients were shown to have coinherited HbH-Constant Spring/QS with a ?-thalassemia mutation. Coinheritance of the ?-thalassemia gene does not alleviate anemia (8.2 ± 2.3 vs. 7.6 ± 1.7 g/dl, p = 0.276), or influence age at diagnosis (20.2 ± 19.6 vs. 12.9 ± 11.0 years, p = 0.276). Ferritin levels were significantly higher in the group of patients with the nondeletional form of the disease (475 ± 719 vs. 249 ± 264 ng/ml, p = 0.005).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1421-9662
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pubmed:author |
pubmed-author:ChenYong-ShengYS,
pubmed-author:FangSu-PingSP,
pubmed-author:HeYuan-YuanYY,
pubmed-author:KongXiang-JinXJ,
pubmed-author:LiangBoB,
pubmed-author:LuLi-BiaoLB,
pubmed-author:LuoRui-GuiRG,
pubmed-author:MOREC GCG,
pubmed-author:WangLiL,
pubmed-author:WuZhi-KuiZK,
pubmed-author:YinXiao-LlinXL,
pubmed-author:ZhangTian-LangTL,
pubmed-author:ZhangXin-HuaXH,
pubmed-author:ZhouTian-HongTH,
pubmed-author:ZhouYa-LiYL
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pubmed:copyrightInfo |
Copyright © 2010 S. Karger AG, Basel.
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pubmed:issnType |
Electronic
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pubmed:volume |
124
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
86-91
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pubmed:meshHeading |
pubmed-meshheading:20639625-Adolescent,
pubmed-meshheading:20639625-Adult,
pubmed-meshheading:20639625-Aged,
pubmed-meshheading:20639625-Aged, 80 and over,
pubmed-meshheading:20639625-Asian Continental Ancestry Group,
pubmed-meshheading:20639625-Child,
pubmed-meshheading:20639625-Child, Preschool,
pubmed-meshheading:20639625-China,
pubmed-meshheading:20639625-Female,
pubmed-meshheading:20639625-Ferritins,
pubmed-meshheading:20639625-Genetic Predisposition to Disease,
pubmed-meshheading:20639625-Genotype,
pubmed-meshheading:20639625-Hemoglobin H,
pubmed-meshheading:20639625-Hemoglobinuria,
pubmed-meshheading:20639625-Humans,
pubmed-meshheading:20639625-Infant,
pubmed-meshheading:20639625-Male,
pubmed-meshheading:20639625-Middle Aged,
pubmed-meshheading:20639625-Young Adult,
pubmed-meshheading:20639625-alpha-Thalassemia,
pubmed-meshheading:20639625-beta-Thalassemia
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pubmed:year |
2010
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pubmed:articleTitle |
Hemoglobin H disease in Guangxi province, Southern China: clinical review of 357 patients.
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pubmed:affiliation |
Department of Hematology, 303rd Hospital of PLA, Nanning, Guangxi, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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