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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2010-9-13
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pubmed:abstractText |
Smaller hippocampal volume has repeatedly been reported in schizophrenia patients. Obstetric complications (OCs) and single nucleotide polymorphism (SNP) variation in schizophrenia susceptibility genes have independently been related to hippocampal volume. We investigated putative independent and interaction effects of severe hypoxia-related OCs and variation in four hypoxia-regulated schizophrenia susceptibility genes (BDNF, DTNBP1, GRM3 and NRG1) on hippocampal volume in schizophrenia patients and healthy controls.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1878-4216
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1259-65
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pubmed:meshHeading |
pubmed-meshheading:20638435-Adult,
pubmed-meshheading:20638435-Anoxia,
pubmed-meshheading:20638435-Brain-Derived Neurotrophic Factor,
pubmed-meshheading:20638435-Carrier Proteins,
pubmed-meshheading:20638435-Case-Control Studies,
pubmed-meshheading:20638435-Female,
pubmed-meshheading:20638435-Genotype,
pubmed-meshheading:20638435-Hippocampus,
pubmed-meshheading:20638435-Humans,
pubmed-meshheading:20638435-Image Processing, Computer-Assisted,
pubmed-meshheading:20638435-Magnetic Resonance Imaging,
pubmed-meshheading:20638435-Male,
pubmed-meshheading:20638435-Middle Aged,
pubmed-meshheading:20638435-Neuregulin-1,
pubmed-meshheading:20638435-Obstetric Labor Complications,
pubmed-meshheading:20638435-Polymorphism, Single Nucleotide,
pubmed-meshheading:20638435-Pregnancy,
pubmed-meshheading:20638435-Receptors, Metabotropic Glutamate,
pubmed-meshheading:20638435-Schizophrenia,
pubmed-meshheading:20638435-Young Adult
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pubmed:year |
2010
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pubmed:articleTitle |
An exploratory model for G x E interaction on hippocampal volume in schizophrenia; obstetric complications and hypoxia-related genes.
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pubmed:affiliation |
Department of Clinical Medicine, section Vinderen, University of Oslo, Norway. unn.haukvik@medisin.uio.no
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pubmed:publicationType |
Journal Article
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