Linked Life Data

20637619

Source:http://linkedlifedata.com/resource/pubmed/id/20637619

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
14
pubmed:dateCreated
2010-7-26
pubmed:abstractText
Localizing tactile events in external space is required for essential functions such as orienting, haptic exploration, and goal-directed action in peripersonal space. In order to map somatosensory input into a spatiotopic representation, information about skin location must be integrated with proprioceptive information about body posture. We investigated the neural bases of this tactile remapping mechanism in humans by disrupting neural activity in the putative human homolog of the monkey ventral intraparietal area (hVIP), within the right posterior parietal cortex (rPPC), which is thought to house external spatial representations. Participants judged the elevation of touches on their (unseen) forearm relative to touches on their face. Arm posture was passively changed along the vertical axis, so that elevation judgments required the use of an external reference frame. Single-pulse transcranial magnetic stimulation (TMS) over the rPPC significantly impaired performance compared to a control site (vertex). Crucially, proprioceptive judgments of arm elevation or tactile localization on the skin remained unaffected by rPPC TMS. This selective disruption of tactile remapping suggests a distinct computational process dissociable from pure proprioceptive and somatosensory localization. Furthermore, this finding highlights the causal role of human PPC, putatively VIP, in remapping touch into external space.
pubmed:grant
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1879-0445
pubmed:author
pubmed:copyrightInfo
2010 Elsevier Ltd. All rights reserved.
pubmed:issnType
Electronic
pubmed:day
27
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1304-9
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
The posterior parietal cortex remaps touch into external space.
pubmed:affiliation
Departament de Psicologia Bàsica, Universitat de Barcelona, 08035 Barcelona, Spain.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't