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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1-2
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pubmed:dateCreated |
2010-9-10
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pubmed:abstractText |
Multiple sclerosis (MS) is a chronic inflammatory response against constituents of the central nervous system. It is known that regulatory T cells (Tregs) play a key role in the autoimmune balance and their improper function may facilitate the expansion of autoaggressive T cell clones. Recently, microRNAs (miRNAs) have been involved in autoimmune disorders and their loss-of-function in immune cells was shown to facilitate systemic autoimmune disorders. Here, we analyzed the miRNA expression profile in Tregs from MS-RR.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1872-8421
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pubmed:author |
pubmed-author:BattistiniLucaL,
pubmed-author:BiondaniAndreaA,
pubmed-author:BorsellinoGiovannaG,
pubmed-author:CaniattiLuisaL,
pubmed-author:CastellazziMassimilianoM,
pubmed-author:De SantisGiuseppeG,
pubmed-author:FainardiEnricoE,
pubmed-author:FerracinManuelaM,
pubmed-author:FurlanRobertoR,
pubmed-author:GavioliRiccardoR,
pubmed-author:GranieriEnricoE,
pubmed-author:NegriniMassimoM,
pubmed-author:Rosaria TolaMariaM,
pubmed-author:ZagattiBarbaraB
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pubmed:copyrightInfo |
Copyright © 2010 Elsevier B.V. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
14
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pubmed:volume |
226
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
165-71
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pubmed:dateRevised |
2010-12-7
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pubmed:meshHeading |
pubmed-meshheading:20637509-Adult,
pubmed-meshheading:20637509-Analysis of Variance,
pubmed-meshheading:20637509-Antigens, CD,
pubmed-meshheading:20637509-Coculture Techniques,
pubmed-meshheading:20637509-Female,
pubmed-meshheading:20637509-Flow Cytometry,
pubmed-meshheading:20637509-Gene Expression Profiling,
pubmed-meshheading:20637509-Gene Expression Regulation,
pubmed-meshheading:20637509-Genome-Wide Association Study,
pubmed-meshheading:20637509-Humans,
pubmed-meshheading:20637509-Lymphocyte Activation,
pubmed-meshheading:20637509-Male,
pubmed-meshheading:20637509-MicroRNAs,
pubmed-meshheading:20637509-Middle Aged,
pubmed-meshheading:20637509-Multiple Sclerosis,
pubmed-meshheading:20637509-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:20637509-T-Lymphocytes, Regulatory,
pubmed-meshheading:20637509-Transforming Growth Factor beta
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pubmed:year |
2010
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pubmed:articleTitle |
Altered miRNA expression in T regulatory cells in course of multiple sclerosis.
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pubmed:affiliation |
Section of Neurology, Department of Medical and Surgical Sciences of the Communication and Behaviour, University of Ferrara, Ferrara, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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