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rdf:type |
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lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0017337,
umls-concept:C0086418,
umls-concept:C0185117,
umls-concept:C0249880,
umls-concept:C0384826,
umls-concept:C0525037,
umls-concept:C0809183,
umls-concept:C1417407,
umls-concept:C2911684,
umls-concept:C2936350
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pubmed:issue |
2
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pubmed:dateCreated |
2011-1-31
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pubmed:abstractText |
The pathophysiology underlying the chromosome (Chr) 9p21 locus of atherosclerosis susceptibility is presently unknown. Here, we sought to determine whether protein coding genes in the Chr9p21 region, i.e. cyclin-dependent kinase inhibitors CDKN2B (p15(INK4b)), CDKN2A (p16(INK4a), p14(ARF)) and methylthioadenosine phosphorylase (MTAP) were expressed in human atherosclerotic lesions and whether expression was correlated with lesion composition.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/5'-methylthioadenosine phosphorylase,
http://linkedlifedata.com/resource/pubmed/chemical/Actins,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Differentiation...,
http://linkedlifedata.com/resource/pubmed/chemical/CD68 antigen, human,
http://linkedlifedata.com/resource/pubmed/chemical/CDKN2B protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclin-Dependent Kinase Inhibitor...,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclin-Dependent Kinase Inhibitor...,
http://linkedlifedata.com/resource/pubmed/chemical/Purine-Nucleoside Phosphorylase,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Suppressor Protein p14ARF
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1879-1484
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
214
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
264-70
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pubmed:meshHeading |
pubmed-meshheading:20637465-Actins,
pubmed-meshheading:20637465-Antigens, CD,
pubmed-meshheading:20637465-Antigens, Differentiation, Myelomonocytic,
pubmed-meshheading:20637465-Autopsy,
pubmed-meshheading:20637465-Chromosomes, Human, Pair 9,
pubmed-meshheading:20637465-Coronary Artery Disease,
pubmed-meshheading:20637465-Cyclin-Dependent Kinase Inhibitor p15,
pubmed-meshheading:20637465-Cyclin-Dependent Kinase Inhibitor p16,
pubmed-meshheading:20637465-Endarterectomy,
pubmed-meshheading:20637465-Genetic Predisposition to Disease,
pubmed-meshheading:20637465-HEK293 Cells,
pubmed-meshheading:20637465-Haplotypes,
pubmed-meshheading:20637465-Humans,
pubmed-meshheading:20637465-Immunohistochemistry,
pubmed-meshheading:20637465-Macrophages,
pubmed-meshheading:20637465-Phenotype,
pubmed-meshheading:20637465-Purine-Nucleoside Phosphorylase,
pubmed-meshheading:20637465-RNA, Messenger,
pubmed-meshheading:20637465-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:20637465-Tumor Necrosis Factor-alpha,
pubmed-meshheading:20637465-Tumor Suppressor Protein p14ARF
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pubmed:year |
2011
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pubmed:articleTitle |
Expression of Chr9p21 genes CDKN2B (p15(INK4b)), CDKN2A (p16(INK4a), p14(ARF)) and MTAP in human atherosclerotic plaque.
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pubmed:affiliation |
Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Leipzig, Leipzig, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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