Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2010-7-19
pubmed:abstractText
The interaction between pathogenic microorganisms and their hosts is regulated by reciprocal survival strategies, including competition for essential nutrients. Though paradoxical, mammalian hosts have learned to take advantage of amino acid catabolism for controlling pathogen invasion and, at the same time, regulating their own immune responses. In this way, ancient catabolic enzymes have acquired novel functions and evolved into new structures with highly specialized functions, which go beyond the struggle for survival. In this review, we analyze the evidence supporting a critical role for the metabolism of various amino acids in regulating different steps of both innate and adaptive immunity.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1600-065X
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
236
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
243-64
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Control of immune response by amino acid metabolism.
pubmed:affiliation
Department of Experimental Medicine and Biochemical Sciences, University of Perugia, Perugia, Italy.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't