Linked Life Data

20634809

Source:http://linkedlifedata.com/resource/pubmed/id/20634809

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2010-7-16
pubmed:abstractText
The phage-related chromosomal islands (PRCIs) were first identified in Staphylococcus aureus as highly mobile, superantigen-encoding genetic elements known as the S. aureus pathogenicity islands (SaPIs). These elements are characterized by a specific set of phage-related functions that enable them to use the phage reproduction cycle for their own transduction and inhibit phage reproduction in the process. SaPIs produce many phage-like infectious particles; their streptococcal counterparts have a role in gene regulation but may not be infectious. These elements therefore represent phage satellites or parasites, not defective phages. In this Review, we discuss the shared genetic content of PRCIs, their life cycle and their ability to be transferred across large phylogenetic distances.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1740-1534
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
541-51
pubmed:dateRevised
2010-9-29
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
The phage-related chromosomal islands of Gram-positive bacteria.
pubmed:affiliation
New York University School of Medicine, Kimmel Center for Biology and Medicine, Skirball institute of Biomolecular Medicine, Molecular Pathogenesis Program, 540 First Avenue, New York, New York 10016, USA. Richard.Novick@med.nyu.edu
pubmed:publicationType
Journal Article, Review