Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2010-8-2
pubmed:abstractText
High-risk human papillomavirus (HPV) E6 and E7 oncoproteins are essential factors for HPV-induced carcinogenesis, and for the maintenance of the consequent neoplastic growth. Cellular transformation is achieved by complex interaction of these oncogenes with several cellular factors of cell cycle regulation including p53, Rb, cyclin-CDK complexes, p21 and p27. Both persistent infection with high-risk HPV genotypes and immune dysregulation are associated with increased risk of HPV-induced squamous cell carcinoma.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/20633287-10611684, http://linkedlifedata.com/resource/pubmed/commentcorrection/20633287-10647931, http://linkedlifedata.com/resource/pubmed/commentcorrection/20633287-11423255, http://linkedlifedata.com/resource/pubmed/commentcorrection/20633287-11927276, http://linkedlifedata.com/resource/pubmed/commentcorrection/20633287-11930025, http://linkedlifedata.com/resource/pubmed/commentcorrection/20633287-12441259, http://linkedlifedata.com/resource/pubmed/commentcorrection/20633287-12445664, http://linkedlifedata.com/resource/pubmed/commentcorrection/20633287-12538342, http://linkedlifedata.com/resource/pubmed/commentcorrection/20633287-12768014, http://linkedlifedata.com/resource/pubmed/commentcorrection/20633287-12807943, http://linkedlifedata.com/resource/pubmed/commentcorrection/20633287-12915456, http://linkedlifedata.com/resource/pubmed/commentcorrection/20633287-14559806, http://linkedlifedata.com/resource/pubmed/commentcorrection/20633287-14581569, http://linkedlifedata.com/resource/pubmed/commentcorrection/20633287-14625386, http://linkedlifedata.com/resource/pubmed/commentcorrection/20633287-15187189, http://linkedlifedata.com/resource/pubmed/commentcorrection/20633287-15286780, http://linkedlifedata.com/resource/pubmed/commentcorrection/20633287-15613288, http://linkedlifedata.com/resource/pubmed/commentcorrection/20633287-16084708, http://linkedlifedata.com/resource/pubmed/commentcorrection/20633287-16243236, http://linkedlifedata.com/resource/pubmed/commentcorrection/20633287-16672559, http://linkedlifedata.com/resource/pubmed/commentcorrection/20633287-16814460, http://linkedlifedata.com/resource/pubmed/commentcorrection/20633287-17179099, http://linkedlifedata.com/resource/pubmed/commentcorrection/20633287-17320505, http://linkedlifedata.com/resource/pubmed/commentcorrection/20633287-17320506, http://linkedlifedata.com/resource/pubmed/commentcorrection/20633287-17938014, http://linkedlifedata.com/resource/pubmed/commentcorrection/20633287-18086422, http://linkedlifedata.com/resource/pubmed/commentcorrection/20633287-18234758, http://linkedlifedata.com/resource/pubmed/commentcorrection/20633287-18703475, http://linkedlifedata.com/resource/pubmed/commentcorrection/20633287-9126728, http://linkedlifedata.com/resource/pubmed/commentcorrection/20633287-9872311
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:status
MEDLINE
pubmed:issn
1746-160X
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
14
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Human papillomavirus-mediated carcinogenesis and HPV-associated oral and oropharyngeal squamous cell carcinoma. Part 1: human papillomavirus-mediated carcinogenesis.
pubmed:affiliation
Department of Periodontology and Oral Medicine, University of Limpopo, Medunsa Campus, South Africa. lfeller@ul.ac.za
pubmed:publicationType
Journal Article, Review