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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2010-7-30
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pubmed:abstractText |
Lipocalin 2 is a bacteriostatic protein that binds the siderophore enterobactin, an iron-chelating molecule produced by Escherichia coli (E. coli) that is required for bacterial growth. Infection of the lungs by E. coli is rare despite a frequent exposure to this commensal bacterium. Lipocalin 2 is an effector molecule of the innate immune system and could therefore play a role in hindering growth of E. coli in the lungs.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/20633248-10475571,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20633248-12453412,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20633248-12759437,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20633248-12957834,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20633248-14662866,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20633248-15531878,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20633248-15811456,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20633248-16146540,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20633248-16153241,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20633248-16446425,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20633248-17060628,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20633248-17627888,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20633248-18377768,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20633248-18468549,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20633248-18514728,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20633248-19342674,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20633248-19366914,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20633248-19549579,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20633248-19834550,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20633248-7551392,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20633248-7715424,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20633248-8298140,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20633248-8675096,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20633248-8761444,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20633248-9339356
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1465-993X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
96
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pubmed:dateRevised |
2010-9-30
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pubmed:meshHeading |
pubmed-meshheading:20633248-Acute-Phase Proteins,
pubmed-meshheading:20633248-Animals,
pubmed-meshheading:20633248-Blotting, Western,
pubmed-meshheading:20633248-Disease Models, Animal,
pubmed-meshheading:20633248-Escherichia coli,
pubmed-meshheading:20633248-Escherichia coli Infections,
pubmed-meshheading:20633248-Female,
pubmed-meshheading:20633248-Ferrichrome,
pubmed-meshheading:20633248-Immunity, Innate,
pubmed-meshheading:20633248-Immunohistochemistry,
pubmed-meshheading:20633248-Lipocalins,
pubmed-meshheading:20633248-Lung,
pubmed-meshheading:20633248-Matrix Metalloproteinase 9,
pubmed-meshheading:20633248-Mice,
pubmed-meshheading:20633248-Mice, Inbred C57BL,
pubmed-meshheading:20633248-Mice, Knockout,
pubmed-meshheading:20633248-Oncogene Proteins,
pubmed-meshheading:20633248-Pneumocytes,
pubmed-meshheading:20633248-Pneumonia, Bacterial,
pubmed-meshheading:20633248-Respiratory Mucosa,
pubmed-meshheading:20633248-Siderophores,
pubmed-meshheading:20633248-Time Factors
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pubmed:year |
2010
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pubmed:articleTitle |
Lipocalin 2 is protective against E. coli pneumonia.
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pubmed:affiliation |
Granulocyte Research Laboratory, Rigshospitalet, Copenhagen, Denmark.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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