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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2010-12-24
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pubmed:abstractText |
X-linked lymphoproliferative syndrome (XLP) is a rare immunodeficiency with extreme vulnerability to Epstein-Barr virus (EBV) infection. It presents with fatal infectious mononucleosis, lymphoproliferative disorder, or dysgammaglobulinemia. The majority of affected males have mutations in the SH2D1A/SLAM-associated protein (SAP) gene. We previously generated an antihuman SAP monoclonal antibody (KST-3) for a flow cytometric assay and described the activation of T cells to be necessary for the flow cytometric assessment of the SAP expression using an FITC-conjugated secondary antibody.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1552-4957
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pubmed:author |
pubmed-author:GochoYoshihiroY,
pubmed-author:ImaiKohsukeK,
pubmed-author:IshiiEizaburoE,
pubmed-author:KaneganeHirokazuH,
pubmed-author:KasaiMikioM,
pubmed-author:KiyasuJunichiJ,
pubmed-author:KobayashiChieC,
pubmed-author:MiyawakiToshioT,
pubmed-author:NakazawaYozoY,
pubmed-author:NonoyamaShigeakiS,
pubmed-author:TeruiKiminoriK,
pubmed-author:ZhaoMeinaM
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pubmed:copyrightInfo |
Copyright © 2010 International Clinical Cytometry Society.
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pubmed:issnType |
Electronic
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pubmed:volume |
80
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
8-13
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pubmed:meshHeading |
pubmed-meshheading:20632414-Adolescent,
pubmed-meshheading:20632414-Adult,
pubmed-meshheading:20632414-Base Sequence,
pubmed-meshheading:20632414-CD8-Positive T-Lymphocytes,
pubmed-meshheading:20632414-Case-Control Studies,
pubmed-meshheading:20632414-Child,
pubmed-meshheading:20632414-Child, Preschool,
pubmed-meshheading:20632414-Flow Cytometry,
pubmed-meshheading:20632414-Frameshift Mutation,
pubmed-meshheading:20632414-Hematopoietic Stem Cell Transplantation,
pubmed-meshheading:20632414-Herpesvirus 4, Human,
pubmed-meshheading:20632414-Humans,
pubmed-meshheading:20632414-Infant,
pubmed-meshheading:20632414-Intracellular Signaling Peptides and Proteins,
pubmed-meshheading:20632414-Lymphohistiocytosis, Hemophagocytic,
pubmed-meshheading:20632414-Lymphoproliferative Disorders,
pubmed-meshheading:20632414-Male,
pubmed-meshheading:20632414-Point Mutation,
pubmed-meshheading:20632414-Sequence Deletion,
pubmed-meshheading:20632414-Young Adult
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pubmed:year |
2011
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pubmed:articleTitle |
Early and rapid detection of X-linked lymphoproliferative syndrome with SH2D1A mutations by flow cytometry.
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pubmed:affiliation |
Department of Pediatrics, Graduate School of Medicine, University of Toyama, Toyama, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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