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pubmed-article:20626413pubmed:abstractTextThe Fc receptor-like 3 (FCRL3) molecule, involved in controlling B-cell signalling, may contribute to the autoimmune disease process. Recently, a genome-wide screen detected association of neighbouring gene FCRL5 with Graves' disease (GD). To determine whether FCRL5 represents a further independent B-cell signalling GD susceptibility loci, we screened 12 tag SNPs, capturing all known common variation within FCRL5, in 5192 UK Caucasian GD index cases and controls.lld:pubmed
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pubmed-article:20626413pubmed:articleTitleAssociation of Fc receptor-like 5 (FCRL5) with Graves' disease is secondary to the effect of FCRL3.lld:pubmed
pubmed-article:20626413pubmed:affiliationOxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Headington, Oxford, UK. matthew.simmonds@ocdem.ox.ac.uklld:pubmed
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