Source:http://linkedlifedata.com/resource/pubmed/id/20626413
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2010-11-2
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pubmed:abstractText |
The Fc receptor-like 3 (FCRL3) molecule, involved in controlling B-cell signalling, may contribute to the autoimmune disease process. Recently, a genome-wide screen detected association of neighbouring gene FCRL5 with Graves' disease (GD). To determine whether FCRL5 represents a further independent B-cell signalling GD susceptibility loci, we screened 12 tag SNPs, capturing all known common variation within FCRL5, in 5192 UK Caucasian GD index cases and controls.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1365-2265
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pubmed:author | |
pubmed:copyrightInfo |
© 2010 Blackwell Publishing Ltd.
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pubmed:issnType |
Electronic
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pubmed:volume |
73
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
654-60
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pubmed:meshHeading |
pubmed-meshheading:20626413-Case-Control Studies,
pubmed-meshheading:20626413-European Continental Ancestry Group,
pubmed-meshheading:20626413-Genetic Predisposition to Disease,
pubmed-meshheading:20626413-Graves Disease,
pubmed-meshheading:20626413-Humans,
pubmed-meshheading:20626413-Linkage Disequilibrium,
pubmed-meshheading:20626413-Logistic Models,
pubmed-meshheading:20626413-Middle Aged,
pubmed-meshheading:20626413-Polymorphism, Single Nucleotide,
pubmed-meshheading:20626413-Receptors, Cell Surface,
pubmed-meshheading:20626413-Receptors, Immunologic
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pubmed:year |
2010
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pubmed:articleTitle |
Association of Fc receptor-like 5 (FCRL5) with Graves' disease is secondary to the effect of FCRL3.
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pubmed:affiliation |
Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Headington, Oxford, UK. matthew.simmonds@ocdem.ox.ac.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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