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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2010-11-15
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pubmed:abstractText |
Hypoxic exposure contributes to the phenotypic switching of smooth muscle cells (SMCs), while the mechanisms involved in this process is not yet fully elucidated. Myocardin as a co-actor of serum reaction factor plays a crucial role in differentiation of SMCs. This study was aimed to investigate the role of myocardin in hypoxia-induced phenotypic switching of rat pulmonary arterial SMCs (PASMCs).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1096-0945
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010. Published by Elsevier Inc.
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pubmed:issnType |
Electronic
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pubmed:volume |
89
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
301-6
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pubmed:meshHeading |
pubmed-meshheading:20621093-Animals,
pubmed-meshheading:20621093-Blotting, Western,
pubmed-meshheading:20621093-Cell Differentiation,
pubmed-meshheading:20621093-Cell Hypoxia,
pubmed-meshheading:20621093-Cells, Cultured,
pubmed-meshheading:20621093-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:20621093-Gene Expression,
pubmed-meshheading:20621093-Gene Expression Regulation,
pubmed-meshheading:20621093-Immunohistochemistry,
pubmed-meshheading:20621093-Myocytes, Smooth Muscle,
pubmed-meshheading:20621093-Nuclear Proteins,
pubmed-meshheading:20621093-Phenotype,
pubmed-meshheading:20621093-Platelet-Derived Growth Factor,
pubmed-meshheading:20621093-Pulmonary Artery,
pubmed-meshheading:20621093-Rats,
pubmed-meshheading:20621093-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:20621093-Trans-Activators
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pubmed:year |
2010
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pubmed:articleTitle |
Contribution of myocardin in the hypoxia-induced phenotypic switching of rat pulmonary arterial smooth muscle cells.
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pubmed:affiliation |
Institute of Pathology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan 430030, PR China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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