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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7-8
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pubmed:dateCreated |
2010-8-4
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pubmed:abstractText |
Cisplatin-induced nephrotoxicity is associated with increased oxidative stress and inflammatory cytokines in the kidney. Epigallocatechin-3-gallate (EGCG) has anti-oxidant, anti-inflammatory, and anti-tumorigenic properties. In this study, we investigated the effects of EGCG on cisplatin-induced nephrotoxicity and potential mechanisms by which it enhances antioxidant activities and resolves inflammation after EGCG treatment during cisplatin-induced nephrotoxicity.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/4-hydroxy-2-nonenal,
http://linkedlifedata.com/resource/pubmed/chemical/Aldehydes,
http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Antioxidants,
http://linkedlifedata.com/resource/pubmed/chemical/Catalase,
http://linkedlifedata.com/resource/pubmed/chemical/Catechin,
http://linkedlifedata.com/resource/pubmed/chemical/Cisplatin,
http://linkedlifedata.com/resource/pubmed/chemical/Glutathione,
http://linkedlifedata.com/resource/pubmed/chemical/Glutathione Peroxidase,
http://linkedlifedata.com/resource/pubmed/chemical/Heme Oxygenase-1,
http://linkedlifedata.com/resource/pubmed/chemical/NF-E2-Related Factor 2,
http://linkedlifedata.com/resource/pubmed/chemical/NF-kappa B,
http://linkedlifedata.com/resource/pubmed/chemical/Superoxide Dismutase,
http://linkedlifedata.com/resource/pubmed/chemical/Tea,
http://linkedlifedata.com/resource/pubmed/chemical/epigallocatechin gallate
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1879-0631
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pubmed:author |
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pubmed:copyrightInfo |
Copyright (c) 2010 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
14
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pubmed:volume |
87
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
240-5
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pubmed:meshHeading |
pubmed-meshheading:20619277-Aldehydes,
pubmed-meshheading:20619277-Animals,
pubmed-meshheading:20619277-Antineoplastic Agents,
pubmed-meshheading:20619277-Antioxidants,
pubmed-meshheading:20619277-Catalase,
pubmed-meshheading:20619277-Catechin,
pubmed-meshheading:20619277-Cisplatin,
pubmed-meshheading:20619277-Glutathione,
pubmed-meshheading:20619277-Glutathione Peroxidase,
pubmed-meshheading:20619277-Heme Oxygenase-1,
pubmed-meshheading:20619277-Kidney,
pubmed-meshheading:20619277-Male,
pubmed-meshheading:20619277-NF-E2-Related Factor 2,
pubmed-meshheading:20619277-NF-kappa B,
pubmed-meshheading:20619277-Neoplasms,
pubmed-meshheading:20619277-Rats,
pubmed-meshheading:20619277-Rats, Wistar,
pubmed-meshheading:20619277-Signal Transduction,
pubmed-meshheading:20619277-Superoxide Dismutase,
pubmed-meshheading:20619277-Tea
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pubmed:year |
2010
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pubmed:articleTitle |
Epigallocatechin-3-gallate activates Nrf2/HO-1 signaling pathway in cisplatin-induced nephrotoxicity in rats.
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pubmed:affiliation |
Department of Animal Nutrition, Faculty of Veterinary Science, Firat University, Elazig, Turkey. nsahinkm@yahoo.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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