Linked Life Data

20618853

Source:http://linkedlifedata.com/resource/pubmed/id/20618853

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2010-8-11
pubmed:databankReference
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/GQ984147, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/GQ984148, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/GQ984149, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/GQ984150, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/GQ984151, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/GQ984152, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/GQ984153, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/GQ984154, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/GQ984155, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/GQ984156, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/GU457021, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/GU457022, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/GU457023
pubmed:abstractText
Members of the Bacillus cereus group are closely related bacteria that exhibit highly divergent pathogenic properties. Sequencing of Bacillus thuringiensis ssp. kurstaki strain YBT-1520 revealed an increased number of insertion sequences (ISs) compared with those of the published B. cereus group genomes. Although some of these ISs have been observed and summarized in B. thuringiensis previously, a genomic characterization of their content is required to reveal their distribution and evolution. The result shows that the larger number of transposase coding genes on YBT-1520 chromosome is mainly caused by the amplification of IS231C, IS232A and ISBth166. Some functional genes have been disrupted through the insertion of ISs, preferentially IS231C. By comparing the Southern hybridization profiles of different B. thuringiensis strains, the existence of ISBth166 was mainly found in serovar kurstaki and the recent expansion of IS231C between different kurstaki isolates was suggested. In addition to revealing the ISs profile in YBT-1520 as well as the comparison in the B. cereus group, this study will contribute to further comparative analyses of multiple B. thuringiensis strains aimed at understanding the IS-mediated genomic rearrangements among them.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1574-6968
pubmed:author
pubmed:issnType
Electronic
pubmed:day
1
pubmed:volume
310
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
9-16
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Prevalence and diversity of insertion sequences in the genome of Bacillus thuringiensis YBT-1520 and comparison with other Bacillus cereus group members.
pubmed:affiliation
State Key Laboratory of Agricultural Microbiology and National Engineering Research Center of Microbial Pesticides, Huazhong Agricultural University, Wuhan, Hubei, China.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't