Linked Life Data

20618427

Source:http://linkedlifedata.com/resource/pubmed/id/20618427

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2010-7-12
pubmed:abstractText
Convulsive status epilepticus (CSE) is the most common medical neurologic emergency in childhood. It is associated with significant mortality and morbidity. The estimates for the frequencies of adverse outcomes have a very wide range, but even the lower estimates are clinically important. The major predictor of outcomes following CSE is etiology. The characteristics of the episode of CSE itself, for example, seizure length and type, are relatively poor predictors. Nevertheless, there is a relationship between CSE and hippocampal injury. This relationship is well established in animal models, and there is some prospective evidence from human studies that CSE (particularly prolonged febrile seizure) can cause acute hippocampal abnormalities. Further study is required to establish the clinical relevance of these acute findings and to determine whether they predict later mesial temporal sclerosis associated with temporal lobe epilepsy.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1528-1167
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
51 Suppl 3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
178-81
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Adverse outcomes following convulsive status epilepticus in children: relationship with hippocampal injury.
pubmed:affiliation
UCL Institute of Child Health, Great Ormond Street Hospital NHS Trust, London, United Kingdom. rscott@ich.ucl.ac.uk
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't