Source:http://linkedlifedata.com/resource/pubmed/id/20610145
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2010-7-8
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pubmed:abstractText |
Rats display behavioral signs of neuropathic pain lasting for months in the chronic constriction injury (CCI) model. During intrathecal anesthesia, the administered drugs mainly diffuse directly into the superficial neurons in the spinal dorsal horn. This study aimed to investigate the effect of bath application of norepinephrine on whole cell patch clamp recordings from spinal cord slices of CCI rats with allodynia.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0929-6646
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pubmed:author | |
pubmed:copyrightInfo |
Copyright (c) 2010 Formosan Medical Association & Elsevier. Published by Elsevier B.V. All rights reserved.
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pubmed:issnType |
Print
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pubmed:volume |
109
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
438-45
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pubmed:meshHeading |
pubmed-meshheading:20610145-Adrenergic alpha-Antagonists,
pubmed-meshheading:20610145-Animals,
pubmed-meshheading:20610145-Idazoxan,
pubmed-meshheading:20610145-Male,
pubmed-meshheading:20610145-Norepinephrine,
pubmed-meshheading:20610145-Posterior Horn Cells,
pubmed-meshheading:20610145-Rats,
pubmed-meshheading:20610145-Rats, Wistar,
pubmed-meshheading:20610145-Sciatic Neuropathy,
pubmed-meshheading:20610145-Spinal Cord
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pubmed:year |
2010
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pubmed:articleTitle |
Norepinephrine can act via alpha(2)-adrenoceptors to reduce the hyper-excitability of spinal dorsal horn neurons following chronic nerve injury.
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pubmed:affiliation |
Department of Anaesthesiology, Beijing Friendship Hospital affiliated to Capital Medical University, Beijing, China.
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pubmed:publicationType |
Journal Article
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