Source:http://linkedlifedata.com/resource/pubmed/id/20605589
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2011-3-28
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pubmed:abstractText |
Kallikrein-kinin system (KKS) plays an important role in inflammation, ischemia-reperfusion (IR) injury, and development of neoplasia. There is evidence to suggest that KKS plays an important role in organ protection during preconditioning. Aprotinin is a nonspecific serine protease inhibitor, which has been extensively used in cardiac surgery for the control of post operative bleeding. The anti-inflammatory effects of aproprotin are due to its inhibitory effect on the kallikrein-kinin system (KKS). We herein review KKS and its role as applied to the practice of surgery.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1095-8673
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pubmed:author | |
pubmed:copyrightInfo |
Crown Copyright © 2011. Published by Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
167
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
70-7
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pubmed:meshHeading |
pubmed-meshheading:20605589-Aprotinin,
pubmed-meshheading:20605589-Humans,
pubmed-meshheading:20605589-Ischemic Preconditioning, Myocardial,
pubmed-meshheading:20605589-Kallikrein-Kinin System,
pubmed-meshheading:20605589-Myocardial Reperfusion Injury,
pubmed-meshheading:20605589-Neoplasms,
pubmed-meshheading:20605589-Postoperative Hemorrhage
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pubmed:year |
2011
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pubmed:articleTitle |
Kallikrein-kinin system: a surgical perspective in post-aprotinin era.
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pubmed:affiliation |
School of Surgery, University of Western Australia, Perth, Australia.
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
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