Linked Life Data

20603226

Source:http://linkedlifedata.com/resource/pubmed/id/20603226

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
17-18
pubmed:dateCreated
2010-9-13
pubmed:abstractText
Here, we review three 'D's--drugs, delivery systems and devices--that can selectively target not only brain regions but also abnormal cells in the epileptic nervous system. This review also offers insights into the novel molecular targets that enabled the development of new antiepileptic drugs with improved efficacy. Nanotechnology-based delivery systems and alert, diagnostic, surgical and brain stimulation devices designed for the control and management of epilepsy are also discussed. Although the application of the three 'D's continues to be valuable, this review also considers computer-aided software systems, with special emphasis on seizure detection and management. Finally, challenges that still loiter in the field and future prospects that, once accomplished, could lead to cures for epilepsy are addressed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1878-5832
pubmed:author
pubmed:copyrightInfo
Copyright © 2010. Published by Elsevier Ltd.
pubmed:issnType
Electronic
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
717-32
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Insights into the novel three 'D's of epilepsy treatment: drugs, delivery systems and devices.
pubmed:affiliation
Department of Pharmaceutics, Faculty of Pharmacy, Hamdard University, New Delhi 110062, India. shadab.ahmad1@gmail.com
pubmed:publicationType
Journal Article, Review