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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2010-10-4
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pubmed:abstractText |
Nonsteroidal anti-inflammatory drugs (NSAIDs) are effective cancer chemopreventive agents. However, chronic administration of NSAIDs is associated with significant side effects, mainly of the gastrointestinal tract. Given these limitations, we synthesized phospho-sulindac (P-S; OXT-328), a novel sulindac derivative.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1528-0012
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 AGA Institute. Published by Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
139
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1320-32
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pubmed:dateRevised |
2011-10-3
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pubmed:meshHeading |
pubmed-meshheading:20600034-Acetyltransferases,
pubmed-meshheading:20600034-Animals,
pubmed-meshheading:20600034-Antineoplastic Agents,
pubmed-meshheading:20600034-Biogenic Polyamines,
pubmed-meshheading:20600034-Cell Line, Tumor,
pubmed-meshheading:20600034-Colonic Neoplasms,
pubmed-meshheading:20600034-Dinoprostone,
pubmed-meshheading:20600034-Eflornithine,
pubmed-meshheading:20600034-Female,
pubmed-meshheading:20600034-Humans,
pubmed-meshheading:20600034-Mice,
pubmed-meshheading:20600034-Mice, Inbred C57BL,
pubmed-meshheading:20600034-NF-kappa B,
pubmed-meshheading:20600034-Organophosphorus Compounds,
pubmed-meshheading:20600034-Oxidative Stress,
pubmed-meshheading:20600034-Rats,
pubmed-meshheading:20600034-Rats, Sprague-Dawley,
pubmed-meshheading:20600034-Sulindac
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pubmed:year |
2010
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pubmed:articleTitle |
Phospho-sulindac (OXT-328), a novel sulindac derivative, is safe and effective in colon cancer prevention in mice.
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pubmed:affiliation |
Division of Cancer Prevention, Department of Medicine, Stony Brook University, Stony Brook, New York 11794-8173, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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