|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
2010-12-3
|
|
pubmed:abstractText |
Hypoxia inducible factor (HIF) prolyl hydroxylase inhibitors are protective in mouse models of inflammatory bowel disease (IBD). Here, we investigated the therapeutic target(s) and mechanism(s) involved.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
|
pubmed:issn |
1528-0012
|
|
pubmed:author |
pubmed-author:CarmelietPeterP,
pubmed-author:CumminsEoin PEP,
pubmed-author:FallonPadraic GPG,
pubmed-author:FraislPeterP,
pubmed-author:KissJuditJ,
pubmed-author:LasitschkaFelixF,
pubmed-author:LenihanColin RCR,
pubmed-author:MaxwellPatrick HPH,
pubmed-author:MollenhauerMartinM,
pubmed-author:SaundersSean PSP,
pubmed-author:SchneiderMartinM,
pubmed-author:ScholzCarsten CCC,
pubmed-author:StauchMarkusM,
pubmed-author:TambuwalaMurtaza MMM,
pubmed-author:TaylorCormac TCT
|
|
pubmed:copyrightInfo |
Copyright © 2010 AGA Institute. Published by Elsevier Inc. All rights reserved.
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
139
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
2093-101
|
|
pubmed:meshHeading |
pubmed-meshheading:20600011-Animals,
pubmed-meshheading:20600011-Anoxia,
pubmed-meshheading:20600011-Apoptosis,
pubmed-meshheading:20600011-Colitis,
pubmed-meshheading:20600011-Dextran Sulfate,
pubmed-meshheading:20600011-Dioxygenases,
pubmed-meshheading:20600011-Disease Models, Animal,
pubmed-meshheading:20600011-Enterocytes,
pubmed-meshheading:20600011-Epithelial Cells,
pubmed-meshheading:20600011-Humans,
pubmed-meshheading:20600011-Intestinal Absorption,
pubmed-meshheading:20600011-Intestinal Mucosa,
pubmed-meshheading:20600011-Mice,
pubmed-meshheading:20600011-Mice, 129 Strain,
pubmed-meshheading:20600011-Mice, Knockout,
pubmed-meshheading:20600011-Nuclear Proteins,
pubmed-meshheading:20600011-Procollagen-Proline Dioxygenase,
pubmed-meshheading:20600011-Severity of Illness Index
|
|
pubmed:year |
2010
|
|
pubmed:articleTitle |
Loss of prolyl hydroxylase-1 protects against colitis through reduced epithelial cell apoptosis and increased barrier function.
|
|
pubmed:affiliation |
The Conway Institute, University College Dublin, Ireland.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
