Linked Life Data

2059989

Source:http://linkedlifedata.com/resource/pubmed/id/2059989

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2-3
pubmed:dateCreated
1991-8-8
pubmed:abstractText
Several different types of endothelial cells are now known to respond to agonist stimulation with oscillations of cytosolic free [Ca2+] ([Ca2+]i). The oscillations can be repetitive [Ca2+]i spikes or sinusoidal-like oscillations according to the type of endothelial cell. Several properties of these oscillations are described including the effect of removal of extracellular Ca2+ and of changes in membrane potential, and the spatial heterogeneity of the oscillations. Results obtained with human umbilical vein endothelial cells are assessed in relation to a model for [Ca2+]i oscillations that involves Ca(2+)-induced Ca2+ release. In some preparations the oscillations are synchronized in neighbouring cells, whereas in other preparations they are not. The degree of synchrony may have functional implications and this is discussed with respect to control of blood flow and transmural permeability. A third functional implication of oscillations, their possible effect on desensitization, is also discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0143-4160
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
127-34
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:articleTitle
Calcium oscillations in endothelial cells.
pubmed:affiliation
Division of Biomedical Sciences, King's College, London, UK.
pubmed:publicationType
Journal Article, Review