20596538

Source:http://linkedlifedata.com/resource/pubmed/id/20596538

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0001675, umls-concept:C0017262, umls-concept:C0185117, umls-concept:C0205217, umls-concept:C1327413, umls-concept:C1336636, umls-concept:C1707455, umls-concept:C2911684
pubmed:issue	6
pubmed:dateCreated	2010-7-2
pubmed:abstractText	An increasing number of patients have medical conditions with altered host immunity or that require immunosuppressive medications. While immunosuppression is associated with increased risk of infection, the precise effect of immunosuppression on innate immunity is not well understood. We studied monocyte Toll-like receptor (TLR) expression and cytokine production in 137 patients with autoimmune diseases who were maintained on immunosuppressive medications and 419 non-immunosuppressed individuals.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/AR049610, http://linkedlifedata.com/resource/pubmed/grant/AR050498, http://linkedlifedata.com/resource/pubmed/grant/M01-RR00125, http://linkedlifedata.com/resource/pubmed/grant/N01-AI-50031, http://linkedlifedata.com/resource/pubmed/grant/P30AG21342, http://linkedlifedata.com/resource/pubmed/grant/R01 AR049610-10, http://linkedlifedata.com/resource/pubmed/grant/R37-AI-049200-09S1
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/101285081
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Cytokines, http://linkedlifedata.com/resource/pubmed/chemical/Toll-Like Receptor 4
pubmed:status	MEDLINE
pubmed:issn	1932-6203
pubmed:author	pubmed-author:AlloreHeather GHG, pubmed-author:BockenstedtLinda KLK, pubmed-author:BucalaRichardR, pubmed-author:ChenShuS, pubmed-author:DunneDana WDW, pubmed-author:FikrigErolE, pubmed-author:LengLinL, pubmed-author:MalawistaStephen ESE, pubmed-author:MizueYukaY, pubmed-author:MontgomeryRuth RRR, pubmed-author:PiecychnaMartaM, pubmed-author:ShawAlbertA, pubmed-author:TowleVirginiaV, pubmed-author:ZhangLinL
pubmed:issnType	Electronic
pubmed:volume	5
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	e11343
pubmed:dateRevised	2011-4-28
pubmed:meshHeading	pubmed-meshheading:20596538-Adult, pubmed-meshheading:20596538-Cytokines, pubmed-meshheading:20596538-Enzyme-Linked Immunosorbent Assay, pubmed-meshheading:20596538-Female, pubmed-meshheading:20596538-Humans, pubmed-meshheading:20596538-Immunocompetence, pubmed-meshheading:20596538-Immunocompromised Host, pubmed-meshheading:20596538-Male, pubmed-meshheading:20596538-Middle Aged, pubmed-meshheading:20596538-Toll-Like Receptor 4
pubmed:year	2010
pubmed:articleTitle	Increased TLR4 expression and downstream cytokine production in immunosuppressed adults compared to non-immunosuppressed adults.
pubmed:affiliation	Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, United States of America. dana.dunne@yale.edu
pubmed:publicationType	Journal Article, Comparative Study, Research Support, N.I.H., Extramural