Linked Life Data

2059112

Source:http://linkedlifedata.com/resource/pubmed/id/2059112

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1991-7-26
pubmed:abstractText
It is well known that people with spinal cord injuries can develop hypothermia when exposed to an unusually cold environment. Hypothermia can also develop during inpatient rehabilitation, particularly as a side effect of certain medications. We present a patient with C4 incomplete spinal cord injury whose core body temperature was chronically subnormal, and who developed acute hypothermia on several occasions during inpatient rehabilitation. The results of tests of his autonomic function were abnormal. Acute hypothermia (core temperature approximately 34C) was induced when he was challenged with nifedipine. The serum level of phenytoin became elevated to toxic levels during two episodes of acute hypothermia, but the serum level of carbamazepine did not change appreciably. This case demonstrates that people with spinal cord injuries are at risk for hypothermia, that hypothermia can be induced by nifedipine, and that significant thermal challenges can occur during routine inpatient rehabilitation. In addition, hypothermia appears to affect the metabolism of phenytoin.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0003-9993
pubmed:author
pubmed:issnType
Print
pubmed:volume
72
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
421-4
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Acute and chronic hypothermia in a man with spinal cord injury: environmental and pharmacologic causes.
pubmed:affiliation
British Columbia Rehabilitation Society, G.F. Strong Centre, Vancouver, Canada.
pubmed:publicationType
Journal Article, Case Reports