20590601

Source:http://linkedlifedata.com/resource/pubmed/id/20590601

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0018787, umls-concept:C0022116, umls-concept:C0028778, umls-concept:C0035126, umls-concept:C0037473, umls-concept:C0073379, umls-concept:C0205322, umls-concept:C0521116
pubmed:issue	5
pubmed:dateCreated	2010-7-1
pubmed:abstractText	Current strategies to ameliorate cardiac ischaemic and reperfusion damage, including block of the sodium-hydrogen exchanger, are therapeutically ineffective. Here we propose a different approach, block of the persistent sodium current (INaP).
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/7502536
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Calcium, http://linkedlifedata.com/resource/pubmed/chemical/Riluzole, http://linkedlifedata.com/resource/pubmed/chemical/Sodium Channels
pubmed:status	MEDLINE
pubmed:month	Jul
pubmed:issn	1476-5381
pubmed:author	pubmed-author:BenoistDD, pubmed-author:SaintD ADA, pubmed-author:TennLL, pubmed-author:WeissSS, pubmed-author:WhiteEE
pubmed:issnType	Electronic
pubmed:volume	160
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1072-82
pubmed:dateRevised	2011-8-1
pubmed:meshHeading	pubmed-meshheading:20590601-Action Potentials, pubmed-meshheading:20590601-Animals, pubmed-meshheading:20590601-Calcium, pubmed-meshheading:20590601-Dose-Response Relationship, Drug, pubmed-meshheading:20590601-Electrocardiography, pubmed-meshheading:20590601-Heart, pubmed-meshheading:20590601-Male, pubmed-meshheading:20590601-Membrane Potentials, pubmed-meshheading:20590601-Myocardial Reperfusion Injury, pubmed-meshheading:20590601-Myocytes, Cardiac, pubmed-meshheading:20590601-Rats, pubmed-meshheading:20590601-Rats, Sprague-Dawley, pubmed-meshheading:20590601-Rats, Wistar, pubmed-meshheading:20590601-Riluzole, pubmed-meshheading:20590601-Sodium Channels, pubmed-meshheading:20590601-Swine, pubmed-meshheading:20590601-Ventricular Dysfunction, Left
pubmed:year	2010
pubmed:articleTitle	Riluzole protects against cardiac ischaemia and reperfusion damage via block of the persistent sodium current.
pubmed:affiliation	The John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia.
pubmed:publicationType	Journal Article