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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2010-12-2
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pubmed:abstractText |
As is known for many types of human cancers, the hepatocellular carcinoma (HCC) associated with chronic liver disease shows an obvious multistage process of tumor progression. Despite the demonstrated importance of cell-cycle regulators in tumor biology, there have only been a few studies of their role in multistep hepatocarcinogenesis. Recently, we reported that a high level of p27(Kip1) expression is evident from the very early stages of hepatocarcinogenesis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1534-4681
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3386-93
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pubmed:meshHeading |
pubmed-meshheading:20589433-Adult,
pubmed-meshheading:20589433-Aged,
pubmed-meshheading:20589433-Carcinoma, Hepatocellular,
pubmed-meshheading:20589433-Case-Control Studies,
pubmed-meshheading:20589433-Cyclin-Dependent Kinase Inhibitor p27,
pubmed-meshheading:20589433-Disease Progression,
pubmed-meshheading:20589433-Female,
pubmed-meshheading:20589433-Follow-Up Studies,
pubmed-meshheading:20589433-Humans,
pubmed-meshheading:20589433-Immunoenzyme Techniques,
pubmed-meshheading:20589433-Intracellular Signaling Peptides and Proteins,
pubmed-meshheading:20589433-Liver,
pubmed-meshheading:20589433-Liver Cirrhosis,
pubmed-meshheading:20589433-Liver Neoplasms,
pubmed-meshheading:20589433-Male,
pubmed-meshheading:20589433-Middle Aged,
pubmed-meshheading:20589433-Neoplasm Staging,
pubmed-meshheading:20589433-Peptide Hydrolases,
pubmed-meshheading:20589433-Precancerous Conditions,
pubmed-meshheading:20589433-Prognosis,
pubmed-meshheading:20589433-RNA, Messenger,
pubmed-meshheading:20589433-RNA, Neoplasm,
pubmed-meshheading:20589433-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:20589433-S-Phase Kinase-Associated Proteins
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pubmed:year |
2010
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pubmed:articleTitle |
Jun activation domain binding protein 1 is overexpressed from the very early stages of hepatocarcinogenesis.
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pubmed:affiliation |
Department of Surgery, Faculty of Medicine, Kagawa University, Kagawa, Japan. syachida@kms.ac.jp
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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