Linked Life Data

2058482

Source:http://linkedlifedata.com/resource/pubmed/id/2058482

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1991-7-29
pubmed:abstractText
Cranial MR imaging was performed on nine patients (13-27 years old) with classical phenylketonuria in order to define the spectrum of abnormal findings and to determine if these could be related to clinical or biochemical findings. MR abnormalities consistent with demyelination were found in varying degrees in a distribution corresponding to previous histopathologic studies. Specifically, increased signal was seen on T2-weighted sequences, most marked in the periventricular deep cerebral white matter. These changes were more prominent posteriorly, especially about the optic radiations. Comparison with clinical history and MR findings in this small series revealed that patients with adequate dietary control of phenylalanine levels had less severe white matter abnormalities than did patients with poorly controlled phenylalanine intake.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0195-6108
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
403-6
pubmed:dateRevised
2008-2-14
pubmed:meshHeading
pubmed:articleTitle
MR imaging of phenylketonuria.
pubmed:affiliation
Department of Radiology, University of Washington School of Medicine, Seattle 98195.
pubmed:publicationType
Journal Article