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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
98
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pubmed:dateCreated |
2010-6-29
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pubmed:abstractText |
Crohn's disease frequency has increased in recent years in Iran. Genetic and environmental factors predispose people to this disease. Mutation in Caspase Recruitment Domain 15 (CARD15) gene is the most well known genetic predisposing factor to this disease. Frequency of three common CARD15 mutations has been studied in different ethnic groups. We aimed to study the frequency of these mutations in Iranian patients affected with Crohn's Disease.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0172-6390
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pubmed:author |
pubmed-author:GhoddosiAlirezaA,
pubmed-author:Hajizadeh-SikaroodiShohrehS,
pubmed-author:KamaliEsmatE,
pubmed-author:MalekzadehFatemehF,
pubmed-author:MalekzadehRezaR,
pubmed-author:MollahajianHamidH,
pubmed-author:OlfatiGolrokhG,
pubmed-author:RashtakShahroozS,
pubmed-author:TabrizianTahminehT,
pubmed-author:Teimoori-ToolabiLadanL,
pubmed-author:VahediHomayounH,
pubmed-author:ZeinaliSirousS
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pubmed:issnType |
Print
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pubmed:volume |
57
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
275-82
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pubmed:meshHeading |
pubmed-meshheading:20583427-Adult,
pubmed-meshheading:20583427-Case-Control Studies,
pubmed-meshheading:20583427-Crohn Disease,
pubmed-meshheading:20583427-DNA Mutational Analysis,
pubmed-meshheading:20583427-Female,
pubmed-meshheading:20583427-Genetic Predisposition to Disease,
pubmed-meshheading:20583427-Humans,
pubmed-meshheading:20583427-Iran,
pubmed-meshheading:20583427-Male,
pubmed-meshheading:20583427-Mutation,
pubmed-meshheading:20583427-Nod2 Signaling Adaptor Protein,
pubmed-meshheading:20583427-Polymerase Chain Reaction,
pubmed-meshheading:20583427-Polymorphism, Restriction Fragment Length
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pubmed:articleTitle |
Three common CARD15 mutations are not responsible for the pathogenesis of Crohn's disease in Iranians.
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pubmed:affiliation |
Digestive Disease Research Center (DDRC), Shariati Hospital, Tehran University, Medical Sciences North Kargar Street, Tehran, Iran 14117-13135. liosha1380@yahoo.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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