20583134

Source:http://linkedlifedata.com/resource/pubmed/id/20583134

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0021467, umls-concept:C0021469, umls-concept:C0027651, umls-concept:C0376358, umls-concept:C0540511, umls-concept:C0547047, umls-concept:C0598934
pubmed:issue	16
pubmed:dateCreated	2010-10-28
pubmed:abstractText	Angiopoietin-2 is expressed in prostate cancer (PCa) bone, liver, and lymph node metastases, whereas, its competitor angiopoietin-1 has limited expression in these tissues. Therefore, we hypothesized that the inhibition of angiopoietin-2 activity in PCa will impede angiogenesis, tumor growth, and alter bone response in vivo.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/P50CA097186
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8101368
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Angiopoietin-2, http://linkedlifedata.com/resource/pubmed/chemical/DNA Primers, http://linkedlifedata.com/resource/pubmed/chemical/Prostate-Specific Antigen, http://linkedlifedata.com/resource/pubmed/chemical/Receptor, TIE-2
pubmed:status	MEDLINE
pubmed:month	Dec
pubmed:issn	1097-0045
pubmed:author	pubmed-author:CoreyEvaE, pubmed-author:DowellAlexA, pubmed-author:FanslowWilliam CWC, pubmed-author:KoreckijTheodore DTD, pubmed-author:LakelyBryceB, pubmed-author:MorrisseyColmC, pubmed-author:NguyenHollyH, pubmed-author:TrueLawrence DLD, pubmed-author:VessellaRobert LRL
pubmed:copyrightInfo	© 2010 Wiley-Liss, Inc.
pubmed:issnType	Electronic
pubmed:day	1
pubmed:volume	70
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1799-808
pubmed:dateRevised	2011-6-1
pubmed:meshHeading	pubmed-meshheading:20583134-Angiopoietin-2, pubmed-meshheading:20583134-Animals, pubmed-meshheading:20583134-Bone Neoplasms, pubmed-meshheading:20583134-Cell Division, pubmed-meshheading:20583134-Cell Survival, pubmed-meshheading:20583134-DNA Primers, pubmed-meshheading:20583134-Humans, pubmed-meshheading:20583134-Male, pubmed-meshheading:20583134-Mice, pubmed-meshheading:20583134-Mice, SCID, pubmed-meshheading:20583134-Microcirculation, pubmed-meshheading:20583134-Polymerase Chain Reaction, pubmed-meshheading:20583134-Prostate, pubmed-meshheading:20583134-Prostate-Specific Antigen, pubmed-meshheading:20583134-Prostatic Neoplasms, pubmed-meshheading:20583134-Receptor, TIE-2, pubmed-meshheading:20583134-Skin Neoplasms, pubmed-meshheading:20583134-Tibia, pubmed-meshheading:20583134-Transplantation, Heterologous
pubmed:year	2010
pubmed:articleTitle	Inhibition of angiopoietin-2 in LuCaP 23.1 prostate cancer tumors decreases tumor growth and viability.
pubmed:affiliation	Department of Urology, University of Washington, Seattle, WA 98195, USA. cmorriss@u.washington.edu
pubmed:publicationType	Journal Article, Research Support, N.I.H., Extramural