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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
18
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pubmed:dateCreated |
1978-6-12
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pubmed:abstractText |
Studies were done to determine the cause for hypocalcemia, secondary hyperparathyroidism, osteomalacia and osteitis fibrosa cystica in a 22-year-old black woman. The patient had normal serum 25-hydroxyvitamin D (14 ng per milliliter) and markedly elevated serum 1,25-dihydroxyvitamin D (137 pg per milliliter). Vitamin D3, 4000 units per day for four weeks, increased the serum 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D to as high as 29 and 297 pg per milliliter, respectively, and corrected the hypocalcemia and secondary hyperparathyroidism. The results suggest that the disorder results from impaired end-organ response to 1,25-dihydroxyvitamin D. We propose that the entity be called vitamin-D-dependent rickets Type II.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0028-4793
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
4
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pubmed:volume |
298
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
996-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:205789-Adult,
pubmed-meshheading:205789-Dihydroxycholecalciferols,
pubmed-meshheading:205789-Female,
pubmed-meshheading:205789-Humans,
pubmed-meshheading:205789-Hydroxycholecalciferols,
pubmed-meshheading:205789-Hyperparathyroidism, Secondary,
pubmed-meshheading:205789-Hypocalcemia,
pubmed-meshheading:205789-Hypophosphatemia, Familial,
pubmed-meshheading:205789-Osteomalacia,
pubmed-meshheading:205789-Vitamin D
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pubmed:year |
1978
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pubmed:articleTitle |
Vitamin-D-dependent rickets type II. Resistance of target organs to 1,25-dihydroxyvitamin D.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Case Reports
|