Linked Life Data

20577981

Source:http://linkedlifedata.com/resource/pubmed/id/20577981

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2010-6-29
pubmed:abstractText
MRI allows for absolute temperature measurements in substances containing two spectral resonances of which the frequency difference Delta f(T) is related to absolute temperature. This frequency difference can be extracted from spectroscopic data. An image-based MR technique that allows for the acquisition of spectroscopic data at high temporal and spatial resolution is the multi-gradient-echo sequence. In this work, the application of the multi-gradient-echo sequence for MR thermometry purposes was further developed. We investigated the possibility of postprocessing the multi-gradient-echo data into absolute temperature maps, using time-domain analysis of the magnitude of the multi-gradient-echo signals. In this approach, instead of an indirect computation of Delta f(T) from separately found frequencies, Delta f(T) is a direct output parameter. In vitro experiments were performed to provide proof of concept for retrieving absolute temperature maps from the time-domain analysis of multi-gradient-echo magnitude images. It is shown that this technique is insensitive to both field drift and local field disturbances. Furthermore, ex vivo bone marrow experiments were performed, using the fat resonance as a reference for absolute temperature mapping. It is shown that the postprocessing based on the magnitude signal in the time domain allows for the determination of Delta f(T) in bone marrow.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1522-2594
pubmed:author
pubmed:copyrightInfo
(c) 2010 Wiley-Liss, Inc.
pubmed:issnType
Electronic
pubmed:volume
64
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
239-48
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Absolute MR thermometry using time-domain analysis of multi-gradient-echo magnitude images.
pubmed:affiliation
Image Sciences Institute/Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands. sara@isi.uu.nl
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't