|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
17-18
|
|
pubmed:dateCreated |
2010-7-12
|
|
pubmed:abstractText |
BRAF is the most frequently mutated oncogene in melanoma with BRAF(V600E) mutation accounting for 92% of all BRAF variants. As this event occurs early in melanoma progression, the quantification of BRAF-mutated alleles in plasma may represent a useful biomarker for noninvasive diagnosis and prediction of response to therapy.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Sep
|
|
pubmed:issn |
1873-3492
|
|
pubmed:author |
|
|
pubmed:copyrightInfo |
Copyright 2010 Elsevier B.V. All rights reserved.
|
|
pubmed:issnType |
Electronic
|
|
pubmed:day |
6
|
|
pubmed:volume |
411
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1319-24
|
|
pubmed:meshHeading |
pubmed-meshheading:20576522-Adult,
pubmed-meshheading:20576522-Aged,
pubmed-meshheading:20576522-Aged, 80 and over,
pubmed-meshheading:20576522-Alleles,
pubmed-meshheading:20576522-Base Sequence,
pubmed-meshheading:20576522-Cell-Free System,
pubmed-meshheading:20576522-DNA, Neoplasm,
pubmed-meshheading:20576522-DNA Primers,
pubmed-meshheading:20576522-Female,
pubmed-meshheading:20576522-Humans,
pubmed-meshheading:20576522-Male,
pubmed-meshheading:20576522-Melanoma,
pubmed-meshheading:20576522-Middle Aged,
pubmed-meshheading:20576522-Polymerase Chain Reaction,
pubmed-meshheading:20576522-Proto-Oncogene Proteins B-raf,
pubmed-meshheading:20576522-Skin Neoplasms
|
|
pubmed:year |
2010
|
|
pubmed:articleTitle |
Allele specific Taqman-based real-time PCR assay to quantify circulating BRAFV600E mutated DNA in plasma of melanoma patients.
|
|
pubmed:affiliation |
Department of Clinical Physiopathology, University of Florence, Viale Pieraccini 6, 50139 Florence, Italy. p.pinzani@dfc.unifi.it
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
