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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2010-8-17
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pubmed:abstractText |
A common genetic variation at the IL28 locus has been found to affect the response of peg-interferon and ribavirin combination therapy against chronic hepatitis C virus (HCV) infection. An allele associated with a favorable response (rs8099917 T), which is the major allele in the majority of Asian, American, and European populations, has also been found to be associated with spontaneous eradication of the virus.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0168-8278
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pubmed:author |
pubmed-author:AbeHiromiH,
pubmed-author:ArihiroKojiK,
pubmed-author:ChayamaKazuakiK,
pubmed-author:HayesC NelsonCN,
pubmed-author:HiragaNobuhikoN,
pubmed-author:ImamuraMichioM,
pubmed-author:KállayJJ,
pubmed-author:KuboMichiakiM,
pubmed-author:MaekawaToshiroT,
pubmed-author:MikiDaikiD,
pubmed-author:MitsuiFukikoF,
pubmed-author:NakamuraYusukeY,
pubmed-author:OchiHidenoriH,
pubmed-author:TakahashiShoichiS,
pubmed-author:TsugeMasatakaM
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pubmed:copyrightInfo |
Copyright 2010 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.
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pubmed:issnType |
Print
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pubmed:volume |
53
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
439-43
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pubmed:meshHeading |
pubmed-meshheading:20576307-Adult,
pubmed-meshheading:20576307-Aged,
pubmed-meshheading:20576307-Aged, 80 and over,
pubmed-meshheading:20576307-Amino Acid Substitution,
pubmed-meshheading:20576307-Base Sequence,
pubmed-meshheading:20576307-DNA Primers,
pubmed-meshheading:20576307-Female,
pubmed-meshheading:20576307-Hepacivirus,
pubmed-meshheading:20576307-Hepatitis C, Chronic,
pubmed-meshheading:20576307-Host-Pathogen Interactions,
pubmed-meshheading:20576307-Humans,
pubmed-meshheading:20576307-Interleukins,
pubmed-meshheading:20576307-Liver,
pubmed-meshheading:20576307-Male,
pubmed-meshheading:20576307-Middle Aged,
pubmed-meshheading:20576307-Polymorphism, Single Nucleotide,
pubmed-meshheading:20576307-Viral Core Proteins,
pubmed-meshheading:20576307-Young Adult,
pubmed-meshheading:20576307-gamma-Glutamyltransferase
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pubmed:year |
2010
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pubmed:articleTitle |
Common variation of IL28 affects gamma-GTP levels and inflammation of the liver in chronically infected hepatitis C virus patients.
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pubmed:affiliation |
Laboratory for Digestive Diseases, Center for Genomic Medicine, RIKEN, Hiroshima, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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