|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
2010-6-25
|
|
pubmed:abstractText |
In some of our patients with intellectual disability (ID) and sleep problems, the initial good response to melatonin disappeared within a few weeks after starting treatment, while the good response returned only after considerable dose reduction. The cause for this loss of response to melatonin is yet unknown. We hypothesise that this loss of response is associated with slow melatonin metabolism.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
1365-2788
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
54
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
547-55
|
|
pubmed:dateRevised |
2011-11-17
|
|
pubmed:meshHeading |
pubmed-meshheading:20576063-Child,
pubmed-meshheading:20576063-Child, Preschool,
pubmed-meshheading:20576063-Drug Tolerance,
pubmed-meshheading:20576063-Female,
pubmed-meshheading:20576063-Humans,
pubmed-meshheading:20576063-Intellectual Disability,
pubmed-meshheading:20576063-Male,
pubmed-meshheading:20576063-Melatonin,
pubmed-meshheading:20576063-Metabolic Clearance Rate,
pubmed-meshheading:20576063-Middle Aged,
pubmed-meshheading:20576063-Saliva,
pubmed-meshheading:20576063-Sleep Initiation and Maintenance Disorders
|
|
pubmed:year |
2010
|
|
pubmed:articleTitle |
Loss of response to melatonin treatment is associated with slow melatonin metabolism.
|
|
pubmed:affiliation |
's Heeren Loo Zuid-Veluwe, Wekerom, Postbus 75, 6710 BB Ede, The Netherlands. Wiebe.Braam@sheerenloo.nl
|
|
pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
|
