Linked Life Data

20575631

Source:http://linkedlifedata.com/resource/pubmed/id/20575631

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2010-6-25
pubmed:abstractText
To investigate whether a drug interaction exists between bortezomib and the cytochrome P450 (CYP) 3A4 inhibitor itraconazole and/or the CYP2C19 inhibitor lansoprazole that results in increased severity of bortezomib-induced peripheral neuropathy and thrombocytopenia.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1875-9114
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
30
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
661-5
pubmed:meshHeading
pubmed-meshheading:20575631-Adult, pubmed-meshheading:20575631-Aged, pubmed-meshheading:20575631-Boronic Acids, pubmed-meshheading:20575631-Clinical Trials as Topic, pubmed-meshheading:20575631-Dexamethasone, pubmed-meshheading:20575631-Drug Interactions, pubmed-meshheading:20575631-Female, pubmed-meshheading:20575631-Humans, pubmed-meshheading:20575631-Itraconazole, pubmed-meshheading:20575631-Japan, pubmed-meshheading:20575631-Male, pubmed-meshheading:20575631-Middle Aged, pubmed-meshheading:20575631-Multiple Myeloma, pubmed-meshheading:20575631-Peripheral Nervous System Diseases, pubmed-meshheading:20575631-Pyrazines, pubmed-meshheading:20575631-Recurrence, pubmed-meshheading:20575631-Retrospective Studies, pubmed-meshheading:20575631-Thrombocytopenia, pubmed-meshheading:20575631-Treatment Outcome
pubmed:year
2010
pubmed:articleTitle
Drug interaction between itraconazole and bortezomib: exacerbation of peripheral neuropathy and thrombocytopenia induced by bortezomib.
pubmed:affiliation
Department of Pharmacy, Mie University Hospital, Tsu, Mie, Japan.
pubmed:publicationType
Journal Article