Linked Life Data

20566395

Source:http://linkedlifedata.com/resource/pubmed/id/20566395

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
32
pubmed:dateCreated
2010-7-21
pubmed:abstractText
Single-dose vaccine formats can prevent clinic-level vaccine wastage but may incur higher production, medical waste disposal, and storage costs than multi-dose formats. To help guide vaccine developers, manufacturers, distributors, and purchasers, we developed a computational model to predict the potential economic impact of various single-dose versus multi-dose measles (MEA), hemophilus influenzae type B (Hib), Bacille Calmette-Guérin (BCG), yellow fever (YF), and pentavalent (DTP-HepB-Hib) vaccine formats. Lower patient demand favors fewer dose formats. The mean daily patient arrival thresholds for each vaccine format are as follows: for the MEA vaccine, 2 patients/day (below which the single-dose vial and above which the 10-dose vial are least costly); BCG vaccine, 6 patients/day (below, 10-dose vial; above, 20-dose vial); Hib vaccine, 5 patients/day (below, single-dose vial; above, 10-dose vial); YF vaccine, 33 patients/day (below, 5-dose vials; above 50-dose vial); and DTP-HepB-Hib vaccine, 5 patients/day (below, single-dose vial; above, 10-dose vial).
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/20566395-10593026, http://linkedlifedata.com/resource/pubmed/commentcorrection/20566395-10743280, http://linkedlifedata.com/resource/pubmed/commentcorrection/20566395-14755229, http://linkedlifedata.com/resource/pubmed/commentcorrection/20566395-14758432, http://linkedlifedata.com/resource/pubmed/commentcorrection/20566395-16997036, http://linkedlifedata.com/resource/pubmed/commentcorrection/20566395-17901213, http://linkedlifedata.com/resource/pubmed/commentcorrection/20566395-19146901, http://linkedlifedata.com/resource/pubmed/commentcorrection/20566395-6339554, http://linkedlifedata.com/resource/pubmed/commentcorrection/20566395-6556154, http://linkedlifedata.com/resource/pubmed/commentcorrection/20566395-6562087, http://linkedlifedata.com/resource/pubmed/commentcorrection/20566395-9342890
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1873-2518
pubmed:author
pubmed:copyrightInfo
(c) 2010 Elsevier Ltd. All rights reserved.
pubmed:issnType
Electronic
pubmed:day
19
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
5292-300
pubmed:dateRevised
2011-8-1
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Single versus multi-dose vaccine vials: an economic computational model.
pubmed:affiliation
Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA. BYL1@pitt.edu
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural